Spatial Cognitive Mapping

Spatial cognitive mapping is the brain’s ability to build, store, and use internal representations of locations and relationships among objects, allowing people to navigate and orient themselves. It depends on integrating sensory cues, movement, memory, and environmental landmarks through coordinated activity in networks that include the hippocampus and entorhinal cortex, where place and grid cell activity helps encode position and spatial structure. In medicine, studying spatial cognitive mapping supports assessment of memory and navigation deficits in conditions such as Alzheimer’s disease, informs research on brain injury and neurodegeneration, and may guide behavioral testing and interventions aimed at preserving cognitive function.

Spatial Cognitive Mapping - Related Videos

Research

JoVE Journal - Environment

Using Pharmacological Manipulation and High-precision Radio Telemetry to Study the Spatial Cognition in Free-ranging Animals

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Cited by 2 •

2016

This paper describes a novel protocol that combines the pharmacological manipulation of memory and radio telemetry to document and quantify the role of cognition in navigation.

Research

JoVE Journal - Developmental Biology
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Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

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2017

The segmentation clock drives oscillatory gene expression across the pre-somitic mesoderm (PSM). Dynamic Notch activity is key to this process. We use imaging and computational analyses to extract temporal dynamics from spatial expression data to demonstrate that Delta ligand and Notch receptor expression oscillate in the vertebrate PSM.

Research

JoVE Journal - Behavior
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The (Spatial) Memory Game: Testing the Relationship Between Spatial Language, Object Knowledge, and Spatial Cognition

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Cited by 19 •

2018

We present a protocol to explore the relationship between spatial language production, spatial memory, and object knowledge. The procedure allows experimental manipulation of, and control over, conditions of object knowledge, language at instruction, and physical location, thus teasing apart cognitive and linguistic models describing interactions between these variables.

Research

JoVE Journal - Biochemistry
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Spatial Molecular Imaging of the Glycome Using Mass Spectrometry

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Cited by 1 •

2025

This protocol details the key steps to enable rigorous and reproducible measurement of both glycogen and N-linked glycans using mass spectrometry imaging.

Education

JoVE Science Education - Psychology

An Introduction to Cognition

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2023

Cognition encompasses mental processes such as memory, perception, decision-making reasoning and language. Cognitive scientists are using a combination of behavioral and neuropsychological techniques to investigate the underlying neural substrates of cognition. They are interested in understanding how information is perceived, processed and how does it affect the final execution of behaviors. With this knowledge, researchers hope to develop new treatments for individuals with cognitive...

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