Trans-diaphragmatic Access
Trans-diaphragmatic Access - Related Videos
05:04
Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access
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Cited by 4 •
2020
This protocol describes the implantation of human coronary stents into the abdominal aorta of rats with an apoE-/- background using a trans-femoral access. Compared with other animal models, murine models carry the advantages of high throughput, reproducibility, ease of handling and housing, and a broad availability of molecular markers.
05:51
Diaphragmatic Ultrasound in Adults: Image Acquisition and Interpretation
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Cited by 2 •
2025
Point-of-care ultrasound (POCUS) is an essential technique for screening for diaphragmatic dysfunction due to its portability, non-invasiveness, and real-time imaging capabilities. Although current diaphragmatic POCUS protocols exist, they suffer from poor interoperator reliability and lack consensus guidelines. Here we describe a technique that is reproducible and simple to perform.
03:21
Trans-Spinal Direct Current Stimulation of a Rat's Spinal Motoneuron
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2025
This video describes the in vivo intracellular recording of rat motoneurons under trans-spinal direct current stimulation. The protocol describes how to measure membrane properties and record the rhythmic firing of motoneurons before, during, and after anodal or cathodal polarization of the spinal cord.
14:37
Accessibility to Clinical Care for People who use Wheelchairs
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2023
Source: Yetsa Tuakli-Wosornu1,2, Jaideep Talwalkar1; 1Yale School of Medicine, 2University of Pittsburgh In the United States, 25% of the general population suffers from one or another type of disability. Ambulatory disabilities, or mobility impairments, represent the most common subcategory, comprising 14% of the country's populace. Different mobility-assistive devices, ranging from canes to scooters, enable increased independence and improved quality of life for those suffering from mobility...
11:49
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
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Cited by 19 •
2013
We describe a valuable diagnostic assay that could potentially be used to decide the withdrawal of immunosuppression after transplant without elevated risk of graft rejection. The assay uses the principles of Delayed Type Hypersensitivity and provides accurate assessment of both donor specific effector and regulatory immune responses mounted by recipients.
FAQs
The diaphragm forms a boundary between the thoracic and abdominal cavities, so crossing it places nearby structures from both regions within the operative field. Precise anatomical guidance helps the surgeon plan the entry site and control the opening, reducing the risk of injury while preserving the intended route to the target structure.
A controlled opening can create a direct operative route to selected lesions, organs, or spaces located near the thoracoabdominal boundary. This connection may allow instruments to reach a target without relying on access through only one cavity. Its value therefore depends on the target’s position and the need for biopsy, drainage, or resection.
Repair restores the diaphragm after the surgeon has completed the planned intervention. Because the muscle separates the thoracic and abdominal cavities and contributes to their normal anatomical arrangement, closing the operative opening helps reestablish that separation and supports recovery of the diaphragm’s function following access.
Planning begins by identifying a lesion, organ, or space near the diaphragm that may benefit from a cross-cavity route. The surgeon then determines how to create and control the diaphragmatic opening, uses direct visualization and specialized instruments during the operation, and prepares to repair the muscle after completing the biopsy, drainage, or resection.
The approach may support several carefully selected operations, including biopsy to obtain tissue, drainage to address an accessible collection or space, and resection to remove a targeted lesion. These applications are not interchangeable; the appropriate use depends on the anatomical location of the target and whether the planned treatment requires sampling, evacuation, or removal.
Surgeons may consider it when a lesion, organ, or space lies near the boundary between the thoracic and abdominal cavities and is difficult to reach through either cavity alone. The technique can provide a more direct route, but it requires careful selection, controlled entry, visualization, specialized instruments, and subsequent diaphragmatic repair.