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JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
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Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Article DOI: 10.3791/4454
May 2nd, 2013 •
1, 1, 1
1Department of Surgery, University of Wisconsin-Madison, School of Medicine and Public Health

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May 2nd, 2013

We describe a valuable diagnostic assay that could potentially be used to decide the withdrawal of immunosuppression after transplant without elevated risk of graft rejection. The assay uses the principles of Delayed Type Hypersensitivity and provides accurate assessment of both donor specific effector and regulatory immune responses mounted by recipients.

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