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JoVE Journal
Immunology and Infection

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Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
 

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Article DOI: 10.3791/4454
May 2nd, 2013

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Summary May 2nd, 2013

We describe a valuable diagnostic assay that could potentially be used to decide the withdrawal of immunosuppression after transplant without elevated risk of graft rejection. The assay uses the principles of Delayed Type Hypersensitivity and provides accurate assessment of both donor specific effector and regulatory immune responses mounted by recipients.

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