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Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access
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Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access

DOI:
10.3791/61442-v

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05:04 min

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November 19, 2020

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, , , , , ,
1Division of Cardiology, Angiology, and Critical Care,University Hospital RWTH Aachen, 2Department for Operative Intensive Medicine,University Hospital RWTH Aachen, 3Institute for Pathology “Victor Babes”

Chapters

  • 00:04Introduction
  • 00:50Surgery Preparation
  • 01:27Stent Implantation
  • 03:57Results: Representative Stent Implantation Outcome Evaluation
  • 04:37Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol describes the implantation of human coronary stents into the abdominal aorta of rats with an apoE-/- background using a trans-femoral access. Compared with other animal models, murine models carry the advantages of high throughput, reproducibility, ease of handling and housing, and a broad availability of molecular markers.

Tags

Rat Abdominal AortaTrans-femoral AccessCoronary Stent ImplantationMinimally Invasive ProcedureVascular PathologyOptical Coherence TomographyHistological AnalysisAnesthetized RatFemoral ArteryArteriotomyGuide WireBalloon-mounted Coronary StentAortic BifurcationBalloon Catheter Inflation

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