Autism Spectrum

Autism spectrum refers to a range of neurodevelopmental conditions characterized by differences in social communication, sensory processing, and patterns of restricted or repetitive behavior. These features arise through complex interactions among genetic influences and early brain development, which can affect neural connectivity, information processing, and responses to sensory input. Neuroscience research examines these mechanisms using behavioral studies, brain imaging, electrophysiology, and genetic analysis to understand variation across autistic individuals. This work supports earlier identification, individualized interventions, and improved approaches to education, communication, and support while advancing broader knowledge of how the brain develops and organizes behavior.

Autism Spectrum - Related Videos

Education

JoVE Science Education - Psychology

Executive Function in Autism Spectrum Disorder

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2023

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California Attention, working-memory, planning, impulse control, inhibition, and mental flexibility are important components of human cognition that are often referred to as executive functions. Autism spectrum disorder is a developmental disorder that is characterized by impairments in social interaction, communication, and repetitive behaviors. It is a disorder that lasts a lifetime, and is thought to affect...

Autism Spectrum Disorder

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2025

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment. These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

Research

JoVE Journal - Behavior

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

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Cited by 14 •

2015

We describe how to implement a battery of behavioral tasks to examine the processing and integration of sensory stimuli in children with ASD. The goal is to characterize individual differences in temporal processing of simple auditory and visual stimuli and relate these to higher order perceptual skills like speech perception.

Research

JoVE Journal - Medicine
Free Sample

Eye Tracking Young Children with Autism

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Cited by 93 •

2012

Eye tracking has long been used to study gaze patterns in typically-developing individuals, but recent technological advancements have made its use with clinical populations, including autism, more feasible. While eye-tracking young children with autism can offer insight into early symptom manifestations, it involves methodological challenges. Suggestions for best practices are provided.

Hypoxia Alters miRNAs Levels Involved in Non-Mendelian Inheritance of Autism Spectrum Disorder in Mice

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Cited by 1 •

2025

Here, we present a protocol to induce hypoxia in neonatal mice by delivering them in controlled environments with varying oxygen concentrations. Mouse models subjected to oxygen variations at birth have durably varied the expression of miRNAs involved in the induction of behavioral phenotypic changes such as autism.

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