Intracranial Tumor Imaging
Intracranial Tumor Imaging - Related Videos
12:09
A Novel High-resolution In vivo Imaging Technique to Study the Dynamic Response of Intracranial Structures to Tumor Growth and Therapeutics
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Cited by 14 •
2013
We describe a novel in vivo imaging technique that couples fluorescent chimeric mice with intracranial windows and high-resolution 2-photon microscopy. This imaging platform aids studies of dynamic changes in brain tissue and microvasculature, at a single-cell level, following pathological insults and is adaptable to assess intracranial drug delivery and distribution.
11:09
Establishing Intracranial Brain Tumor Xenografts With Subsequent Analysis of Tumor Growth and Response to Therapy using Bioluminescence Imaging
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Cited by 104 •
2010
Luciferase-modified human brain tumor xenografts can be established intracranially in athymic mice, with subsequent monitoring of tumor growth and response to therapy using bioluminescence imaging. In combination with survival analysis, bioluminescence monitoring is an essential research tool for pre-clinical testing of therapies being considered for treating brain tumors.
01:20
Laser Interstitial Thermal Therapy for Intracranial Tumor Ablation in a Human Patient
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2025
Begin with an anesthetized human patient with an exposed skull. The patient is diagnosed with an intracranial tumor.Drill into the exposed skull to create a hole, generating an access point.Using stereotactic guidance, insert a laser diffusing fiber or LDF along the predetermined path and secure it in place.Transfer the patient to an MRI scanner and connect the LDF to a laser source.Capture MRI images from multiple angles to visualize the fiber path and the tumor.This confirms the LDF’s...
10:52
Stereotactic Intracranial Implantation and In vivo Bioluminescent Imaging of Tumor Xenografts in a Mouse Model System of Glioblastoma Multiforme
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Cited by 42 •
2012
We describe an integrated method for the precise, stereotactic implantation of human glioblastoma multiforme cells into the brains of nude mice and subsequent serial in vivo imaging to monitor growth and response to treatment of the resultant xenografts.
14:08
Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images
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Cited by 31 •
2013
An automated midline shift estimation and intracranial pressure (ICP) pre-screening system based on computed tomography (CT) images for patients with traumatic brain injury (TBI) is proposed using image processing and machine learning techniques.
FAQs
Contrast agents help reveal differences in blood-brain barrier permeability, making certain tumor-related abnormalities more conspicuous on MRI. This added information complements the anatomical detail of noncontrast imaging and can help characterize lesions alongside features such as location, size, tissue properties, edema, and effects on nearby structures. Interpretation therefore combines enhancement patterns with the broader structural context.
CT provides rapid structural images using X-rays, whereas MRI uses magnetic fields and radiofrequency signals to produce detailed views of brain anatomy. This distinction gives the modalities complementary roles rather than making one universally preferable. In intracranial tumor evaluation, the choice can reflect the need for rapid structural assessment or more detailed anatomical characterization, based on the clinical and research context.
Quantitative imaging extracts measurable features from tumor-related images, while multimodal studies combine information from more than one imaging approach. Together, they can support investigations of tumor biology and treatment response beyond visual assessment alone. These approaches are especially valuable in neuroscience research because they connect imaging findings with changes in lesion characteristics and the surrounding brain environment.
Imaging findings help establish where a tumor is located, how large it is, what tissue characteristics it displays, and how it affects adjacent structures. Clinicians can use this information to guide biopsy and surgery planning, while also assessing edema and other structural effects. The resulting anatomical context supports more informed decisions about how a lesion should be approached.
Detailed imaging provides a basis for identifying the tumor and evaluating its relationship to surrounding brain structures before treatment. Those findings can inform radiation planning, while later scans allow clinicians and researchers to monitor changes over time. Comparing imaging examinations during follow-up helps assess the tumor and its treatment response within the broader anatomical context.
In neuroscience, imaging links tumor behavior with brain anatomy and the effects of disease on nearby structures. MRI, CT, quantitative measurements, and multimodal studies can provide complementary evidence about lesion characteristics, edema, tumor biology, and response to treatment. This makes imaging useful not only for clinical planning but also for studying how intracranial tumors interact with the nervous system.