Micropump System

A micropump system is a microscale device that moves precise volumes of liquid through channels, enabling controlled fluid transport in compact laboratory and biomedical platforms. Depending on its design, an actuator generates pressure or displacement that drives flow through microchannels, while valves, membranes, or flow resistance regulate direction and delivery rate. In neuroscience, micropump systems support localized administration of drugs, neurotransmitters, or other solutions, as well as controlled perfusion of neural tissues and microfluidic cultures. Their small size and programmable delivery can improve experimental control, reduce sample use, and enable studies of dose-dependent responses, neural signaling, and potential therapeutic strategies.

Micropump System - Related Videos

Research

JoVE Journal - Bioengineering

A Performance-testing Platform for a Conduction Micropump with an FR-4 Copper-clad Electrode Plate

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Cited by 1 •

2017

This paper presents a protocol for the fabrication of a conduction micropump using symmetric planar electrodes on flame-retardant glass-reinforced epoxy (FR-4) copper-clad laminate (CCL) to test the influence of chamber dimensions on the performance of a conduction micropump.

Drug Microinjection with Electrophysiological Recording in a Rat Brain

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2025

This protocol outlines the assembly and use of an injectrode for precise drug delivery into targeted brain regions of an anesthetized rat, followed by monitoring of neuronal activity through recorded electrical signals.

Fluid Aspiration from Mouse Glomeruli: A Method to Aspirate Glomerular Fluid from Mouse Using Two-Photon Mediated Micropuncture

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2023

This video showcases fluid aspiration from mouse glomeruli using the two-photon mediated micropuncture technique. The technique provides access to the living mouse’s glomeruli and thus helps gain insights into renal physiology.

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

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Cited by 11 •

2017

We present a magnetic levitation technique coupled with automated imaging and analysis in both a smartphone-compatible device and a device with embedded imaging and processing. This is applied to measure the density distribution of cells with two demonstrated biomedical applications: sickle cell disease diagnosis and separating white and red blood cells.

Improving the Application of High Molecular Weight Biotinylated Dextran Amine for Thalamocortical Projection Tracing in the Rat

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2018

Here, we present a refined protocol to effectively reveal biotinylated dextran amine (BDA) labeling with a fluorescent staining method through a reciprocal neural pathway. It is suitable for analyzing the fine structure of BDA labeling and distinguishing it from other neural elements under a confocal laser scanning microscope.

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