George Miller

George A. Miller was an influential psychologist and cognitive scientist whose research helped establish cognitive psychology as the study of mental processes such as memory, attention, and language. His information-processing approach examined how people encode, store, and retrieve limited amounts of information, including his finding that immediate memory commonly holds about seven meaningful units, plus or minus two, depending on how material is organized. Miller showed that chunking, or grouping separate items into larger meaningful units, can expand effective memory capacity. His work shaped theories of working memory, language processing, learning, and human-computer interaction, while providing a foundation for modern cognitive science.

George Miller - Related Videos

Research

JoVE Journal - Chemistry

Conducting Miller-Urey Experiments

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Cited by 16 •

2014

The Miller-Urey experiment was a pioneering study regarding the abiotic synthesis of organic compounds with possible relevance to the origins of life. Simple gases were introduced into a glass apparatus and subjected to an electric discharge, simulating the effects of lightning in the primordial Earth’s atmosphere-ocean system. The experiment was conducted for one week, after which, the samples collected from it were analyzed for the chemical building blocks of life.

Non-invasive Imaging of Leukocyte Homing and Migration in vivo

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Cited by 8 •

2010

Here, we describe a non-invasive two-photon (2P) microscopy approach to study leukocyte homing in the mouse footpad. We discuss the technical aspects of our tissue imaging preparation and walk the reader through a typical experiment from initial set up to execution and data collection.

Research

JoVE Journal - Neuroscience
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Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology

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Cited by 31 •

2010

We provide a reproducible method for culturing confluent monolayers of human fetal retinal pigment epithelial cells (hfRPE) cells that exhibit morphology, physiology, polarity, and protein and gene expression patterns of adult native tissue. This work has been extended to an animal model of several eye diseases.

Transplantation into the Anterior Chamber of the Eye for Longitudinal, Non-invasive In vivo Imaging with Single-cell Resolution in Real-time

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Cited by 31 •

2013

A new approach combining intraocular transplantation and confocal microscopy enables longitudinal, non-invasive real-time imaging with single-cell resolution within grafted tissues in vivo. We demonstrate how to transplant pancreatic islets into the anterior chamber of the mouse eye.

Isolation of Pure Astrocytes and Microglia from the Adult Mouse Spinal Cord For In Vitro Assays and Transcriptomic Studies

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Cited by 1 •

2023

This protocol outlines the isolation of purified astrocytes and microglia from the adult mouse spinal cord, facilitating subsequent applications such as RNA analysis and cell culture. It includes detailed cell dissociation methods and procedures designed to enhance both the quality and yield of isolated cells.

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