Hemisphere Lesions
Hemisphere Lesions - Related Videos
01:05
Cerebral Hemispheres
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2024
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
03:00
Recording of Local Field Potential from Both Hemispheres of the Mouse Brain
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2025
This video demonstrates in vivo recording of local field potential (LFP) from bilateral M2 areas of the mouse brain. An anesthetized mouse is secured and prepared for the procedure. To record LFPs, insert microelectrodes into the target coordinates of the bilateral M2 areas, which are responsible for complex motor movements.
05:47
Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
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Cited by 10 •
2016
We applied repetitive transcranial magnetic stimulation (rTMS) to the unilateral hemisphere of rat brain, by placing a 25-mm figure-8 coil 1 cm lateral to the vertex on the biauricular line and angulating the coil by 45°. An in-house water cooling system was used for rTMS for more than 20 min.
13:47
Ex utero Electroporation and Whole Hemisphere Explants: A Simple Experimental Method for Studies of Early Cortical Development
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Cited by 14 •
2013
This protocol describes an improved explant procedure that involves ex utero electroporation, dissection and culture of entire cerebral hemispheres from the embryonic mouse. The preparation facilitates pharmacological studies and assays of gene function during early cortical development.
09:22
Sectioning Mammary Gland Whole Mounts for Lesion Identification
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Cited by 13 •
2017
We developed a method to successfully remove, process, section, and stain, for histopathological evaluation, mammary tissue that had originally been fixed on slides as whole mounts. This method may promote the collection and evaluation of mammary gland whole mounts in reproductive and developmental test guideline studies.
FAQs
Their effects provide evidence that cognitive and behavioral functions are distributed unevenly across the cerebral hemispheres. When damage affects one side, researchers can examine changes in language, memory, attention, emotion, perception, or movement and relate those changes to the lesion’s location. This approach helps psychology investigate hemispheric specialization without treating the brain as functionally uniform.
Lesion outcomes depend on more than the affected hemisphere. The extent and precise location of damage influence which functions are disrupted, while neural plasticity and compensation can affect later performance. Consequently, two people with damage involving the same broad side of the brain may show different cognitive, emotional, perceptual, or behavioral patterns and different recovery trajectories.
Because each cerebral hemisphere controls much of the opposite side of the body, a lesion can produce effects that appear away from the damaged tissue. This relationship helps clinicians and researchers connect movement changes with brain organization. It also adds a physical dimension to psychological interpretation, allowing motor findings to complement observations of cognition, perception, and behavior.
Changes after a lesion show how the brain may reorganize or compensate when normal function is disrupted. Observing recovery alongside persistent difficulties helps researchers distinguish between functions that remain vulnerable and capacities that can be supported through altered brain organization. These findings contribute to psychological models of recovery, adaptation, and the changing relationship between neural activity and behavior.
Clinical assessment examines the person’s cognitive, emotional, perceptual, behavioral, and movement changes in relation to the lesion’s location and extent. The resulting profile helps identify disrupted functions and supports interpretation of hemispheric specialization. In research, comparing these patterns across individuals provides evidence about brain organization while also informing diagnosis and decisions about rehabilitation planning.
Assessment results identify which functions have been affected and which abilities may remain available to support recovery. Clinicians can use that information to plan rehabilitation around the person’s observed cognitive, emotional, perceptual, behavioral, or movement difficulties. Because lesion extent and neural compensation influence outcomes, follow-up observations are also relevant to adjusting expectations and support.
They connect changes in neural tissue with measurable differences in cognition, emotion, perception, movement, and behavior. This makes lesion evidence useful for testing psychological theories of hemispheric specialization and brain organization. The same evidence also supports practical goals, including diagnosis, rehabilitation planning, and prediction of recovery, linking basic research with clinical understanding of brain function.