Rapid Screening Platform

A rapid screening platform is an integrated system for evaluating large numbers of samples, compounds, or biological signals efficiently, helping researchers make faster, data-informed decisions. In cancer research, it typically combines standardized assays with parallel processing, automated data capture, and analysis of molecular, cellular, or phenotypic readouts to identify meaningful differences between test conditions. These platforms can support drug discovery, biomarker evaluation, and studies of treatment response by prioritizing promising candidates for detailed investigation. By increasing screening capacity while maintaining consistent experimental conditions, they help accelerate early-stage research and clarify which findings warrant validation in more complex models.

Rapid Screening Platform - Related Videos

Research

JoVE Journal - Bioengineering

Field-Deployable Lens-Free Imaging Platform for Rapid Label-Free Analysis of Natural Killer Cell Activation

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Cited by 1 •

2025

This protocol describes a label-free method for the rapid single-cell analysis of natural killer (NK) cell count and activity using lens-free shadow imaging technology. This method quantifies morphological changes in individual NK cells by computerized analysis of their diffraction patterns.

Research

JoVE Journal - Immunology and Infection
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Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

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Cited by 15 •

2014

Here we describe cellular cytotoxicity and single round infectivity assays that allow for the rapid and accurate screening of compounds to determine their cellular cytotoxicity (CC50) and IC50 values against WT and drug resistant HIV-1.

A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells

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Cited by 6 •

2013

Achieving a systems level understanding of cellular processes is a goal of modern-day cell biology. We describe here strategies for multiplexing luciferase reporters of various cellular function end-points to interrogate gene function using genome-scale RNAi libraries.

Research

JoVE Journal - Biology
Free Sample

Automated Modular High Throughput Exopolysaccharide Screening Platform Coupled with Highly Sensitive Carbohydrate Fingerprint Analysis

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Cited by 18 •

2016

We present an automated modular high-throughput-method for the identification and characterization of microbial exopolysaccharides in small scale. This method combines a fast preselection to analyze the total amount of secreted polysaccharides with a detailed carbohydrate fingerprint to enable the fast screening of newly isolated bacterial strains or entire strain collections.

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

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2018

Salmonella spp./Shigella spp. are common pathogens attributed to diarrhea. Here, we describe a high-throughput platform for the screening of Salmonella spp./Shigella spp. using real-time PCR combined with guided culture.

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