Conical Top
Conical Top - Related Videos
01:29
Polar Equations of Conics
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2025
A conic section can be defined in polar coordinates as the set of all points whose distance from a fixed point, known as the focus, bears a constant ratio to their distance from a fixed line, known as the directrix. This constant ratio is called the eccentricity. This definition unifies all types of conic sections—ellipses, parabolas, and hyperbolas—under a single framework. When the focus is positioned at the origin of the polar coordinate system, a single polar equation can describe any conic...
12:10
Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method
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Cited by 35 •
2011
This article describes a standard method to get a three-dimensional (3D) reconstruction of biological macromolecules using negative staining electron microscopy (EM). In this protocol, we explain how to get the 3D structure of the Saccharomyces cerevisiae exosome complex at medium resolution using the random conical tilt reconstruction method (RCT).
05:58
Method for Obtaining Primary Ovarian Cancer Cells From Solid Specimens
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Cited by 13 •
2014
This study describes a detailed method for isolation and characterization of primary ovarian cancer cells from solid clinical specimens. Ovarian cancer clinical specimens are subjected to enzymatic digestion to obtain viable, fibroblast-free epithelial ovarian cancer (EOC) cells highly suitable for downstream applications.
03:42
Obtaining a Single-Cell Suspension from Mouse Hippocampal Tissue
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2025
This video demonstrates a protocol to obtain a highly viable single-cell suspension from the mouse brain hippocampus using a combination of automated mechanical dissociation and a mixture of enzymes to aid in enzymatic digestion.
09:25
Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
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Cited by 68 •
2012
Here, we detail a methodology for the rapid isolation of mouse intestinal dendritic cells (DCs) and macrophages. Phenotypic characterization of intestinal DCs and macrophages is performed using multi-color flow cytometric analysis while magnetic bead enrichment followed by cell sorting is used to yield highly pure populations for functional studies.
FAQs
Changing the cone angle changes how applied loads are redirected and how material travels along the inclined surface. A steeper or shallower profile therefore affects the balance between structural loading, drainage, and discharge behavior. Engineers must evaluate the angle together with the contents and operating conditions rather than treating geometry as an isolated choice.
Material properties determine how liquids, powders, or particles interact with the inclined surfaces, while operating conditions influence the loads and movement the structure must accommodate. These factors can affect accumulation, drainage, discharge, and stability. Considering them together helps engineers select a geometry that performs reliably instead of relying only on the cone shape.
The inclined, narrowing profile provides directional control that a flat or less-tapered section may not provide. It can redirect forces and encourage liquids, powders, particles, or airflow to move toward or away from a central opening. The same geometry may also reduce accumulation, making it useful when movement and drainage are important design goals.
Design begins by identifying the intended function, such as controlling loading, drainage, discharge, or airflow. Engineers then relate the cone angle and overall geometry to the material being handled, expected operating conditions, and required stability. The design should also account for fabrication, because the selected shape must be practical to produce as well as structurally and operationally suitable.
Applications include hoppers, tanks, silos, pressure vessels, roofs, and process equipment. In storage or handling systems, the profile can guide liquids, powders, or particles and limit accumulation. In structural or equipment settings, it can help manage loading, drainage, or airflow. The appropriate application depends on which of these functions the geometry must support.
Engineers can evaluate how the geometry affects stability, structural loading, drainage, discharge, accumulation, and material movement. These outcomes connect the physical shape to operating performance and safety. In practice, examining cone angle, material properties, and conditions together supports more reliable designs for structures and equipment that store, contain, or process materials.