Deep brain stimulation surgery offers a unique opportunity to examine information encoding in the awake human brain. This article will describe intra-operative methods used to perform cognitive and behavioral tasks while simultaneously acquiring physiological data such as EMG, single-unit neuronal activity and/or local field potentials.
Gale, J. T., Martinez-Rubio, C., Sheth, S. A., Eskandar, E. N. Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery. J. Vis. Exp. (47), e2156, doi:10.3791/2156 (2011).