A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 03:48Behavioral Training and Rig Setup
- 05:37Intra-operative – Experimental Setup
- 07:16Isolation of Subthalamic Nucleus Neurons
- 09:28Data Acquisition
- 10:17Lead Implantation and Completion of Surgery
- 10:45Representative DBS Results
- 11:28Conclusion
Deep brain stimulation surgery offers a unique opportunity to examine information encoding in the awake human brain. This article will describe intra-operative methods used to perform cognitive and behavioral tasks while simultaneously acquiring physiological data such as EMG, single-unit neuronal activity and/or local field potentials.
Tags
Intra-operative Behavioral TasksAwake HumansDeep Brain Stimulation SurgerySurgical ProcedureChronic Electrical StimulationImplanted ElectrodesTherapeutic ModalityVentral Intermediate Nucleus Of The ThalamusTremor TreatmentParkinson’s DiseaseDystoniaEssential TremorRandomized Controlled TrialsU.S. Food And Drug AdministrationMedically Refractory Essential TremorMajor Depressive DisorderEpilepsyQuality Of Life ImprovementHuman Brain StudyMicroelectrode Recordings
