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Immunohistochemische kleuring van B7-H1 (PD-L1) op paraffine ingebedde Slides van Pancreatic Darmkanker Tissue
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Immunohistochemische kleuring van B7-H1 (PD-L1) op paraffine ingebedde Slides van Pancreatic Darmkanker Tissue

Article DOI: 10.3791/4059-v • 10:11 min • January 3rd, 2013
January 3rd, 2013 •
1,2, 1,2, 1,2,3, 1, 1,2,4, 3,5, 6, 1,2,5,7,8, 1,2,5,8, 1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine

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B7-H1 (PD-L1) en de binding aan PD-1 een grote tumor geïnduceerde immunosuppressieve signaal in de tumor micro-omgeving. Een immunohistochemische kleuring techniek om de expressie en lokalisatie van B7-H1 in pancreas adenocarcinoom karakteriseren wordt hier beschreven.

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Kankerbiologie geneeskunde immunologie biochemie moleculaire biologie Cellulaire Biologie Scheikunde Oncologie immunohistochemie B7-H1 (PD-L1) pancreas adenocarcinoom pancreaskanker alvleesklier tumor T-cel immuniteit kanker
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