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Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development

Article DOI: 10.3791/4458
January 26th, 2013 •
1, 1, 2
1Department of Biological Sciences, The George Washington University, 2Department of Anatomy and Regenerative Biology, The George Washington University

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January 26th, 2013

The fate of an individual embryonic cell can be influenced by inherited molecules and/or by signals from neighboring cells. Utilizing fate maps of the cleavage stage Xenopus embryo, single blastomeres can be identified for culture in isolation to assess the contributions of inherited molecules versus cell-cell interactions.

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