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Journal / Immunology and Infection / Framställning av tumörantigen-laddade mogna…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Framställning av tumörantigen-laddade mogna dendritceller för Immunotherapy
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Framställning av tumörantigen-laddade mogna dendritceller för Immunotherapy

Article DOI: 10.3791/50085-v • 08:40 min • August 1st, 2013
August 1st, 2013 •
1, 2, 1, 1, 1, 1
1Cancer Institute, NYU Langone Medical Center, 2Infectious Diseases, NYU Langone Medical Center

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Den vanligaste metoden för att generera ett stort antal autologa dendritiska celler (DC) för användning i tumörimmunterapi beskrives. Metoden använder IL-4 och GM-CSF att skilja DCs från monocyter. De omogna DC stimuleras att mogna och sedan lastas med antigener innan de injiceras tillbaka in i patienten.

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Cancer Biology medicin immunologi molekylärbiologi cellbiologi medicinsk teknik anatomi fysiologi dendritiska celler immunterapi dendritiska celler immunterapi vaccin cell isolering flödescytometri cellodling kliniska tekniker
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