This manuscript presents a simple, yet powerful, in vitro method for evaluating smooth muscle contractility in response to pharmacological agents or nerve stimulation. Main applications are drug screening and understanding tissue physiology, pharmacology, and pathology.
Kullmann, F. A., Daugherty, S. L., de Groat, W. C., Birder, L. A. Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology. J. Vis. Exp. (90), e51807, doi:10.3791/51807 (2014).