In this manuscript, experimental techniques, including blood preparation, confocal microscopy, and lysis rate analysis, to examine the morphological differences between normal and abnormal clot structures due to diseased states are presented.
Fan, N. K., Keegan, P. M., Platt, M. O., Averett, R. D. Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States. J. Vis. Exp. (98), e52019, doi:10.3791/52019 (2015).