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Svulst Engraftment i en Xenograft musemodell av menneskelig mantelen celle lymfomer
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
DOI:

10:52 min

March 30, 2018

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Chapters

  • 00:05Title
  • 01:23Preparation of Primary Peripheral Blood Mononuclear Cells by Density Gradient Separation
  • 03:15Enrichment of B Cells Negative Selection
  • 05:34Development of the Xenograft Mouse Model
  • 06:07Chimerism Analysis of Tumor Cell Engrafted in Different Organs
  • 07:43Results: Use of Flow Cytometry to Analyze the B Cell Enrichment in Mice Xenografts Obtained from Mantle Cell Lymphoma Patients
  • 09:08Conclusion

Summary

Automatic Translation

Det er like vanskelig å etablere en xenograft musemodell primære MCL å studere og utvikle therapeutics mantelen celle lymfomer (MCL) er en vanskelig å behandle B celle uorden. Her beskriver vi vellykket etablering av MCL xenografts i mus til å forstå sin underliggende biologi.

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