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JoVE Journal Developmental Biology
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
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An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Article DOI: 10.3791/58476-v • 07:50 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1,2, 3, 3, 3, 4, 1, 5, 2, 1
1Cardiovascular Developmental Biology, Department of Cardiovascular Sciences, KU Leuven, 2Centre for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, 3Department of Biohybrid & Medical Textiles, AME - Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, 4European Homograft Bank, Saint Jean Clinique, 5Division of Clinical Cardiac Surgery, Department of Cardiovascular Sciences, KU Leuven

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Summary
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We describe an in-house designed in vitro flow chamber model, which allows the investigation of bacterial adherence to graft tissues.

Tags

In Vitro Model Parallel-Plate Perfusion System Bacterial Adherence Graft Tissues Pathogenesis Infective Endocarditis Pathobiograms Interplay Between Bacteria Blood Cells Endothelial Cells Tissue Grafts Mutual Interactions Standardized Flow Conditions Therapy Of Infective Endocarditis Molecular Interactions Vegetation Formation Vascular Permeability Cell Mobility Gene Cell Expression
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