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JoVE Journal
Bioengineering

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Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
 

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

Article doi: 10.3791/3958
June 22nd, 2012

Summary June 22nd, 2012

A method to culture an endothelial cell monolayer throughout the entire inner 3D surface of a microfluidic device with microvascular-sized channels (<30 μm) is described. This in vitro microvasculature model enables the study of biophysical interactions between blood cells, endothelial cells, and soluble factors in hematologic diseases.

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