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JoVE Journal
Biochemistry

This content is Open Access.

Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation
 

Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation

Article DOI: 10.3791/61125-v 15:05 min
May 20th, 2020

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Summary May 20th, 2020

The objective of this protocol is to use molecular dynamics simulations to examine the dynamic structural changes that occur due to activating mutations of the EGFR kinase protein.

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