Burkhard Wiesner Leibniz Institute for Molecular Pharmacology (FMP) Biography Publications Institution JoVE Articles Burkhard Wiesner has not added a biography. If you are Burkhard Wiesner and would like to personalize this page please email our Author Liaison for assistance. Publications Small-molecule Screening Identifies Modulators of Aquaporin-2 Trafficking Journal of the American Society of Nephrology : JASN. Apr, 2013 | Pubmed ID: 23559583 Structural Insights into the Mechanism of GTPase Activation in the GIMAP Family Structure (London, England : 1993). Apr, 2013 | Pubmed ID: 23454188 Multivalent Design of Apoptosis-inducing Bid-BH3 Peptide-oligosaccharides Boosts the Intracellular Activity at Identical Overall Peptide Concentrations Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2012 | Pubmed ID: 23124530 The Pseudo Signal Peptide of the Corticotropin-releasing Factor Receptor Type 2A Prevents Receptor Oligomerization The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22689579 Coumarin-based Octopamine Phototriggers and Their Effects on an Insect Octopamine Receptor Chembiochem : a European Journal of Chemical Biology. Jul, 2012 | Pubmed ID: 22674503 Live Cell Imaging of G Protein-coupled Receptors Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22674164 Xirp Proteins Mark Injured Skeletal Muscle in Zebrafish PloS One. 2012 | Pubmed ID: 22355335 Use of Kikume Green-red Fusions to Study the Influence of Pharmacological Chaperones on Trafficking of G Protein-coupled Receptors FEBS Letters. Mar, 2012 | Pubmed ID: 22306118 New Pathogenic Thyrotropin Receptor Mutations Decipher Differentiated Activity Switching at a Conserved Helix 6 Motif of Family A GPCR The Journal of Clinical Endocrinology and Metabolism. Feb, 2012 | Pubmed ID: 22112806 Quantitative Modelling of Amyloidogenic Processing and Its Influence by SORLA in Alzheimer's Disease The EMBO Journal. Jan, 2012 | Pubmed ID: 21989385 Growth Factor- and Adhesion Protein-like Components of Fetal Calf Serum Can Significantly Enhance the Intracellular Delivery of Peptide Nucleic Acids Nucleic Acid Therapeutics. Aug, 2011 | Pubmed ID: 21851222 Inhibition of Biosynthesis of Human Endothelin B Receptor by the Cyclodepsipeptide Cotransin The Journal of Biological Chemistry. Oct, 2011 | Pubmed ID: 21808059 Photocontrol of Contracting Muscle Fibers Angewandte Chemie (International Ed. in English). Aug, 2011 | Pubmed ID: 21739542 Routes of Epithelial Water Flow: Aquaporins Versus Cotransporters Biophysical Journal. Dec, 2010 | Pubmed ID: 21112289 Structural Basis of Oligomerization in Septin-like GTPase of Immunity-associated Protein 2 (GIMAP2) Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21059949 Reciprocal Regulation of Aquaporin-2 Abundance and Degradation by Protein Kinase A and P38-MAP Kinase Journal of the American Society of Nephrology : JASN. Oct, 2010 | Pubmed ID: 20724536 The Pseudo Signal Peptide of the Corticotropin-releasing Factor Receptor Type 2a Decreases Receptor Expression and Prevents Gi-mediated Inhibition of Adenylyl Cyclase Activity The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20682782 Impact of Membrane Properties on Uptake and Transcytosis of Colloidal Nanocarriers Across an Epithelial Cell Barrier Model Journal of Pharmaceutical Sciences. May, 2010 | Pubmed ID: 20014431 Glycogen Synthase Kinase 3beta Interaction Protein Functions As an A-kinase Anchoring Protein The Journal of Biological Chemistry. Feb, 2010 | Pubmed ID: 20007971 Cellular Uptake and Biological Activity of Peptide Nucleic Acids Conjugated with Peptides with and Without Cell-penetrating Ability Journal of Peptide Science : an Official Publication of the European Peptide Society. Jan, 2010 | Pubmed ID: 19943337 Caged Progesterone: a New Tool for Studying Rapid Nongenomic Actions of Progesterone Journal of the American Chemical Society. Mar, 2009 | Pubmed ID: 19256499 Apical Membrane Maturation and Cellular Rosette Formation During Morphogenesis of the Zebrafish Lateral Line Journal of Cell Science. Mar, 2009 | Pubmed ID: 19208766 Use of Kaede Fusions to Visualize Recycling of G Protein-coupled Receptors Traffic (Copenhagen, Denmark). Jan, 2009 | Pubmed ID: 18939954 Interaction of Angiotensin-converting Enzyme (ACE) with Membrane-bound Carboxypeptidase M (CPM) - a New Function of ACE Biological Chemistry. Dec, 2008 | Pubmed ID: 18844448 Nuclear Localization of the Zebrafish Tight Junction Protein Nagie Oko Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jan, 2008 | Pubmed ID: 18058913 Derlin-1 and P97/valosin-containing Protein Mediate the Endoplasmic Reticulum-associated Degradation of Human V2 Vasopressin Receptors Molecular Pharmacology. Mar, 2008 | Pubmed ID: 18048502 {7-[Bis(carboxymethyl)amino]coumarin-4-yl}methoxycarbonyl Derivatives for Photorelease of Carboxylic Acids, Alcohols/phenols, Thioalcohols/thiophenols, and Amines Chemistry (Weinheim an Der Bergstrasse, Germany). 2008 | Pubmed ID: 18046693 Formation of Tight Junction: Determinants of Homophilic Interaction Between Classic Claudins FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2008 | Pubmed ID: 17761522 AKAP Complex Regulates Ca2+ Re-uptake into Heart Sarcoplasmic Reticulum EMBO Reports. Nov, 2007 | Pubmed ID: 17901878 Microtubules Are Needed for the Perinuclear Positioning of Aquaporin-2 After Its Endocytic Retrieval in Renal Principal Cells American Journal of Physiology. Cell Physiology. Sep, 2007 | Pubmed ID: 17626240 Rescue of a Nephrogenic Diabetes Insipidus-causing Vasopressin V2 Receptor Mutant by Cell-penetrating Peptides The Journal of Biological Chemistry. Jul, 2007 | Pubmed ID: 17491025 Increase in Fluidity in the Membrane of MT3 Breast Cancer Cells Correlates with Enhanced Cell Adhesion in Vitro and Increased Lung Metastasis in NOD/SCID Mice Archives of Biochemistry and Biophysics. Mar, 2007 | Pubmed ID: 17222386 A Role of Myosin Vb and Rab11-FIP2 in the Aquaporin-2 Shuttle Traffic (Copenhagen, Denmark). Feb, 2007 | Pubmed ID: 17156409 Compartmentalization of CAMP-dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-mediated Water Reabsorption in Renal Principal Cells Journal of the American Society of Nephrology : JASN. Jan, 2007 | Pubmed ID: 17135396 TIRC7 Inhibits T Cell Proliferation by Modulation of CTLA-4 Expression Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006 | Pubmed ID: 17082597 The Corticotropin-releasing Factor Receptor Type 2a Contains an N-terminal Pseudo Signal Peptide The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16766521 Spatial Organisation of AKAP18 and PDE4 Isoforms in Renal Collecting Duct Principal Cells European Journal of Cell Biology. Jul, 2006 | Pubmed ID: 16500722 Dimerization of Corticotropin-releasing Factor Receptor Type 1 is Not Coupled to Ligand Binding Journal of Receptor and Signal Transduction Research. 2005 | Pubmed ID: 16393915 Coumarinylmethyl Esters for Ultrafast Release of High Concentrations of Cyclic Nucleotides Upon One- and Two-photon Photolysis Angewandte Chemie (International Ed. in English). Dec, 2005 | Pubmed ID: 16270373 Nuclear Export Determines the Cytokine Sensitivity of STAT Transcription Factors The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16195225 Live Cell Imaging of G Protein-coupled Receptors Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 15867469 (Coumarin-4-yl)methyl Esters As Highly Efficient, Ultrafast Phototriggers for Protons and Their Application to Acidifying Membrane Surfaces Angewandte Chemie (International Ed. in English). Feb, 2005 | Pubmed ID: 15696594 Studies on the Cellular Uptake of Substance P and Lysine-rich, KLA-derived Model Peptides Journal of Molecular Recognition : JMR. Jan-Feb, 2005 | Pubmed ID: 15386618 Pharmacochaperones Post-translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-type and Mutant Vasopressin V2 Receptors The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15319430 Enhancement of Intracellular Concentration and Biological Activity of PNA After Conjugation with a Cell-penetrating Synthetic Model Peptide European Journal of Biochemistry / FEBS. Jul, 2004 | Pubmed ID: 15233801 C-FLIP Mediates Resistance of Hodgkin/Reed-Sternberg Cells to Death Receptor-induced Apoptosis The Journal of Experimental Medicine. Apr, 2004 | Pubmed ID: 15078899 Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for Its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15037626 Aquaporin-1, Nothing but a Water Channel The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14701836 DNA Binding Controls Inactivation and Nuclear Accumulation of the Transcription Factor Stat1 Genes & Development. Aug, 2003 | Pubmed ID: 12923054 The Prostaglandin E2 Analogue Sulprostone Antagonizes Vasopressin-induced Antidiuresis Through Activation of Rho Journal of Cell Science. Aug, 2003 | Pubmed ID: 12829746 [7-(Dialkylamino)coumarin-4-yl]methyl-Caged Compounds As Ultrafast and Effective Long-Wavelength Phototriggers of 8-Bromo-Substituted Cyclic Nucleotides Chembiochem : a European Journal of Chemical Biology. May, 2003 | Pubmed ID: 12740815 DMACM-caged Adenosine Nucleotides: Ultrafast Phototriggers for ATP, ADP, and AMP Activated by Long-wavelength Irradiation Chembiochem : a European Journal of Chemical Biology. Mar, 2003 | Pubmed ID: 12616629 Intracellular Calcium Measurements of Single Human Skin Cells After Stimulation with Corticotropin-releasing Factor and Urocortin Using Confocal Laser Scanning Microscopy Journal of Cell Science. Apr, 2003 | Pubmed ID: 12615968 Fluorescence Spectroscopic Quantification of the Release of Cyclic Nucleotides from Photocleavable [bis(carboxymethoxy)coumarin-4-yl]methyl Esters Inside Cells Angewandte Chemie (International Ed. in English). Oct, 2002 | Pubmed ID: 12370911 Dyrkning Primær Rat Inner Medullær samlekanal Cells Dörte Faust1, Andrea Geelhaar1, Beate Eisermann1, Jenny Eichhorst2, Burkhard Wiesner2, Walter Rosenthal1,3, Enno Klussmann1 1Anchored Signalling, Max-Delbrück-Center for Molecular Medicine, 2Leibniz Institute for Molecular Pharmacology (FMP), 3Charité University Medicine Berlin JoVE 50366 Biology
Dyrkning Primær Rat Inner Medullær samlekanal Cells Dörte Faust1, Andrea Geelhaar1, Beate Eisermann1, Jenny Eichhorst2, Burkhard Wiesner2, Walter Rosenthal1,3, Enno Klussmann1 1Anchored Signalling, Max-Delbrück-Center for Molecular Medicine, 2Leibniz Institute for Molecular Pharmacology (FMP), 3Charité University Medicine Berlin JoVE 50366 Biology