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Histological Staining of Spinal Cord for Assessing EAE Disease Severity

February 23rd, 2024
1, 2, 1,2, 3, 1, 1, 2, 2,4, 1,2,5
1Department of Immunology, University of Toronto, 2Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, 3Sickkids Research Institute, The Hospital for Sick Children, 4BARLO MS Centre, St. Michael’s Hospital, 5Women’s College Research Institute, Women’s College Hospital

Summary
Automatic Translation

实验性自身免疫性脑脊髓炎 （EAE） 是多发性硬化症的动物模型。本文介绍了一种对 EAE 中脊髓炎症、脱髓鞘和轴突损伤进行评分的方法。此外，还提出了一种量化小鼠血清中可溶性神经丝光水平的方法，有助于评估活小鼠的轴突损伤。

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