Ventricular Dimension Quantification

Ventricular dimension quantification is the measurement of cardiac ventricle size and geometry, providing objective indicators of heart structure and function. It typically analyzes imaging data, such as echocardiography or magnetic resonance images, to identify ventricular boundaries and calculate dimensions, areas, or volumes at defined points in the cardiac cycle, including end diastole and end systole. In bioengineering, these measurements support assessment of chamber remodeling, contractile performance, and disease progression. They also provide essential parameters for validating computational heart models, evaluating cardiovascular devices, and designing patient-specific diagnostic or therapeutic approaches.

Ventricular Dimension Quantification - Related Videos

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JoVE Journal - Immunology and Infection

Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging

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2025

This study presents a 3D imaging method using whole-mount intestinal tissues and multi-photon microscopy to quantify secreted mucus, enabling precise volumetric analysis and visualization of mucus dynamics in response to stimuli like carbamoylcholine chloride.

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model

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Cited by 16 •

2014

This article provides detailed methodologies for the use of three-dimensional (3D) assays to quantify breast cancer cell invasion. Specifically, we discuss the procedures required to set up such assays, quantification, and data analysis, as well as methods to examine the loss of membrane integrity that occurs when cells invade.

Dendritic Spine Quantification Using an Automatic Three-Dimensional Neuron Reconstruction Software

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Cited by 2 •

2024

Dendritic spines are post-synaptic compartments of most excitatory synapses. Alterations to dendritic spine morphology occur during neurodevelopment, aging, learning, and many neurological and psychiatric disorders, underscoring the importance of reliable dendritic spine analysis. This protocol describes quantifying dendritic spine morphology accurately and reproducibly using automatic three-dimensional neuron reconstruction software.

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

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Cited by 4 •

2018

Here, we present a protocol using two centrifugal pumps as a total artificial heart replacement.

High-Throughput Capable Three-Dimensional Tissue Model for Quantification of Electroporation Thresholds

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Cited by 1 •

2025

This protocol uses computational modeling to quantify reversible and irreversible electroporation thresholds using the spatial distribution of transfected cells within a three-dimensional tissue mimic for high-throughput analysis of electroporation protocols.

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