Lingual Lipase

Lingual lipase is a digestive enzyme produced by glands on the tongue that begins the breakdown of dietary fats. After secretion into saliva, it hydrolyzes triglycerides into fatty acids and smaller lipid molecules, with much of its activity continuing in the acidic environment of the stomach. This early step in lipid digestion is particularly important because it helps prepare fats for later processing by pancreatic lipase in the small intestine. Studying lingual lipase provides insight into digestive physiology, nutrient absorption, and how enzyme activity changes across development or in digestive disorders.

Lingual Lipase - Related Videos

Research

JoVE Journal - Biochemistry

Defining Substrate Specificities for Lipase and Phospholipase Candidates

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Cited by 10 •

2016

Many predicted (phospho)lipases are poorly characterized with regard to their substrate specificities and physiological functions. Here we provide a protocol to optimize enzyme activities, search for natural substrates, and propose physiological functions for these enzymes.

Assessment of Spatial Lingual Tactile Sensitivity using a Gratings Orientation Test

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Cited by 2 •

2021

This work illustrates a standard procedure and threshold determination by the R-index to assess spatial lingual tactile sensitivity using a gratings orientation test.

Research

JoVE Journal - Behavior
Free Sample

Assessment of Midline Lingual Point-Pressure Somatosensation Using Von Frey Hair Monofilaments

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Cited by 9 •

2020

This work describes a standard method to assess tactile sensation at the midline of the tongue tip. Using Von Frey Hair (VFH) monofilaments, this protocol provides estimates of detection and discrimination threshold estimates for oral point pressure (OPP).

Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells

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Cited by 16 •

2021

The protocol presents a method for culturing and processing lingual organoids derived from taste stem cells isolated from the posterior taste papilla of adult mice.

Research

JoVE Journal - Neuroscience
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Mapping and Application of Enhancer-trap Flippase Expression in Larval and Adult Drosophila CNS

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Cited by 7 •

2011

We describe a Flippase-induced intersectional Gal80/Gal4 repression (FINGR) method, allowing tissue-specific FLP to determine Gal80 expression patterns. Wherever Gal4 and FLP overlap, Gal4 expression is turned on (Gal80 flipped out) or off (Gal80 flipped in). The FINGR method is versatile for clonal analysis and neural circuit mapping.

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