Nerve Root Compression

Nerve root compression is a condition in which a spinal nerve root is squeezed or irritated, impairing communication between the spinal cord and the body. It commonly results from a herniated disc, bone spur, or narrowing of the spinal canal; pressure and inflammation disrupt nerve signaling and can produce radiating pain, numbness, tingling, or muscle weakness along the affected nerve pathway. In biology and clinical research, studying this process clarifies how nervous tissue responds to mechanical stress and inflammation. Neurological examination and imaging help identify the compressed root, guide treatment, and assess outcomes such as symptom relief and restored function.

Nerve Root Compression - Related Videos

Research

JoVE Journal - Medicine

Circumferential Transforaminal Endoscopic Lumbar Foraminotomy for 360° Exiting Nerve Root Decompression in Patients with Lumbar Foraminal Stenosis

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2026

This protocol describes circumferential transforaminal endoscopic lumbar foraminotomy for 360° decompression of the exiting nerve root in patients with lumbar foraminal stenosis using a step-by-step, landmark-based approach to achieve adequate bony and soft-tissue decompression.

Retrograde Loading of Nerves, Tracts, and Spinal Roots with Fluorescent Dyes

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Cited by 5 •

2012

We describe a simple and low cost technique for introducing high concentration of fluorescent and calcium-sensitive dyes into neurons or any neuronal tract using a polyethylene suction pipette.

Auditory Nerve Root Stimulation and Postsynaptic Current Recordings in a Mouse Brain Wedge Slice

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2025

This video demonstrates a protocol for stimulating the auditory nerve root and recording postsynaptic currents in medial olivocochlear neurons in mouse brain wedge slices.

Research

JoVE Journal - Medicine

Analgesic Effect of Tuina on Rat Models with Compression of the Dorsal Root Ganglion Pain

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Cited by 4 •

2023

This article presents a manipulation for treating chronic compression of the dorsal root ganglion in rats using Tuina therapy, along with a method for evaluating its effectiveness based on pain behavior and histopathological results.

Research

JoVE Journal - Neuroscience
Free Sample

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

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Cited by 35 •

2015

Dorsal root ganglia (DRG) are structures containing the sensory neurons of the peripheral nervous system. When dissociated, they can be co-cultured with SC-like adipose-derived stem cells (ASC), providing a valuable model to study in vitro nerve regeneration and myelination, mimicking the in vivo environment at the injury site.

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