Cholesterol Polyps
Cholesterol Polyps - Related Videos
09:58
Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
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Cited by 2 •
2014
Vocal fold polyps can disrupt vocal fold dynamics and thus can have devastating consequences on a patient's ability to communicate. Three-dimensional flow separation induced by a wall-mounted model polyp and its impact on the wall pressure loading are examined using particle image velocimetry, skin friction line visualization, and wall pressure measurements.
11:07
Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
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Cited by 22 •
2014
In this article, a protocol for infection of macrophages with Cryptococcus neoformans is described. Also, a method for sterol depletion from the macrophages is explained. These protocols provide a guide to study fungal infections in vitro and examine the role of sterols in such infections.
01:29
Cholesterol: Significance and Regulation
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2024
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces. Considering cholesterol and...
07:54
Cholesterol Efflux Assay
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Cited by 74 •
2012
The cholesterol assay is designed to quantitate the rate of cholesterol efflux from cultured cells and the capacity of plasma acceptors to accept cholesterol released from cells. The assay consists of labelling cells with cholesterol, equilibration of cholesterol among intracellular pools and release of cholesterol to an extracellular acceptor.
10:12
Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
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Cited by 12 •
2020
Two methods of cholesterol enrichment are presented: the application of cyclodextrin saturated with cholesterol to enrich mammalian tissues and cells, and the use of cholesterol-enriched phospholipid-based dispersions (liposomes) to enrich Xenopus oocytes. These methods are instrumental for determining the impact of elevated cholesterol levels in molecular, cellular, and organ function.
FAQs
Macrophages, specialized immune cells in the gallbladder lining, take up excess cholesterol. As cholesterol accumulates within these cells, the affected mucosal area can project from the gallbladder wall. This cellular process explains why the lesions are attached growths rather than freely moving material, helping distinguish them from gallstones during imaging assessment.
Attachment provides an important imaging clue because cholesterol polyps generally remain fixed to the gallbladder wall, whereas gallstones are freely mobile. Clinicians consider this behavior together with size and visual appearance rather than relying on one feature alone. The distinction supports more accurate interpretation of abdominal imaging and helps guide subsequent assessment.
Size, appearance, and change over time are the main features used to identify lesions that may require closer evaluation. Most cholesterol polyps remain benign, but less common neoplastic polyps can carry a higher malignancy risk. A lesion that appears atypical or changes during follow-up may therefore prompt a different management discussion.
Ultrasound surveillance provides repeated assessments of a lesion’s size, appearance, and stability over time. Clinicians use these observations to refine risk assessment rather than treating every detected polyp immediately. Continued stability can support observation, while concerning imaging features or interval change may lead to consideration of gallbladder removal.
Gallbladder removal may be considered when imaging shows features associated with a higher risk of malignancy. Decisions are informed by the polyp’s size, appearance, and behavior during surveillance, not simply by its presence. Because most cholesterol polyps cause no symptoms and remain benign, follow-up is often relevant before an intervention is chosen.
Abdominal imaging can reveal these lesions even when a person has no symptoms. Ultrasound then helps characterize their attachment, size, appearance, and changes over time. That information allows clinicians to distinguish a likely benign cholesterol polyp from a less common neoplastic lesion and to select surveillance or further management according to the assessed risk.