Posterior Intervertebral Fusion
Posterior Intervertebral Fusion - Related Videos
08:03
An In Vitro Organ Culture Model of the Murine Intervertebral Disc
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Cited by 22 •
2017
Whole organ culture of the intervertebral disc (IVD) preserves the native extracellular matrix, cell phenotypes, and cellular-matrix interactions. Here we describe an IVD culture system using mouse lumbar and caudal IVDs in their functional spinal units and several applications utilizing this system.
13:37
Preparation of Intact Bovine Tail Intervertebral Discs for Organ Culture
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Cited by 34 •
2012
This protocol illustrates a harvesting technique for coccygeal bovine intervertebral discs for organ culture for in vitro organ culture.
07:25
Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury
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Cited by 18 •
2017
Intervertebral disc degeneration is a significant contributor to back pain and a leading cause of disability worldwide. Numerous animal models of intervertebral disc degeneration exist. We demonstrate an ovine model of intervertebral disc degeneration, utilizing a drill bit, which achieves a consistent disc injury and reproducible level of disc degeneration.
02:45
Nuclear Fusion
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2020
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons. A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
04:27
Generating a Pro-Inflammatory Organ Culture Model to Simulate an Early Intervertebral Disc Disease
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2025
This video demonstrates a technique for culturing bovine intervertebral discs in bioreactors to develop a three-dimensional organ culture model. Specific nutrient-deprived media and degenerative pressure conditions are applied to the discs, mimicking the pro-inflammatory and degenerative microenvironment observed during early-stage intervertebral disc disease. The disc heights are measured post-treatment to analyze the effects of nutrient deprivation and degenerative loading.
FAQs
Pain relief primarily comes from stopping motion at a diseased or unstable motion segment. Bone graft is placed so that new bone can eventually bridge the adjacent vertebrae, while screws and rods help preserve alignment during healing. This combination addresses both the mechanical source of pain and the loss of structural support rather than relying on decompression alone.
Decompression addresses neural structures when needed, whereas grafting and fixation target stability and eventual fusion. Keeping these purposes distinct helps explain why the operation may include more than one surgical objective: relieving pressure on neural tissues, preparing the intervertebral space, and maintaining alignment while bone healing develops.
Successful bone healing depends on more than the graft itself. Patient selection, surgical technique, preservation of alignment with screws and rods when used, and appropriate postoperative care all influence whether the intended fusion develops. These factors help explain why similar procedures can produce different outcomes clinically.
The workflow generally combines several coordinated steps: reaching the spine through a posterior approach, decompressing neural structures when indicated, preparing the intervertebral space, placing bone graft material, and using screws and rods when needed to maintain alignment. The sequence supports both immediate stabilization and later formation of new bone across the motion segment.
Clinicians may consider posterior intervertebral fusion for selected cases of degenerative disc disease, spinal deformity, or instability. The choice depends on whether the condition produces a need for greater structural support and whether eliminating painful movement could address the clinical problem. Careful patient selection is therefore central to its appropriate use.
Postoperative care supports the conditions required for successful bone healing and helps preserve the alignment established during surgery. Because the intended fusion develops over time rather than immediately, follow-up management is part of the treatment process. Its quality can influence whether structural support is maintained and whether the desired outcome is achieved.