Edward Perez-Reyes Department of Pharmacology University of Virginia Biography Publications Institution JoVE Articles Edward Perez-Reyes has not added a biography. If you are Edward Perez-Reyes and would like to personalize this page please email our Author Liaison for assistance. Publications Effect of Photobiomodulation on Mitochondrial Dynamics in Peripheral Nervous System in Streptozotocin-induced Type 1 Diabetes in Rats Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Feb, 2021 | Pubmed ID: 33721255 A Brainstem Peptide System Activated at Birth Protects Postnatal Breathing Nature. 01, 2021 | Pubmed ID: 33268898 Characterization of Kindled VGAT-Cre Mice As a New Animal Model of Temporal Lobe Epilepsy Epilepsia. 10, 2020 | Pubmed ID: 32954490 Inhibition of T-Type Calcium Channels in MEC Layer II Stellate Neurons Reduces Neuronal Hyperexcitability Associated with Epilepsy Epilepsy Research. 08, 2019 | Pubmed ID: 31132598 Primary Aldosteronism Associated with a Germline Variant in BMJ Case Reports. May, 2019 | Pubmed ID: 31126930 LMO7 Deficiency Reveals the Significance of the Cuticular Plate for Hearing Function Nature Communications. 03, 2019 | Pubmed ID: 30850599 CACHD1 is an α2δ-Like Protein That Modulates Ca3 Voltage-Gated Calcium Channel Activity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 10, 2018 | Pubmed ID: 30181139 A Novel Therapeutic Approach for Treatment of Catamenial Epilepsy Neurobiology of Disease. 03, 2018 | Pubmed ID: 29274741 Functional Variants in and May Contribute to Genetic Generalized Epilepsy Epilepsia Open. 09, 2017 | Pubmed ID: 29588962 Calmodulin Regulates Ca3 T-type Channels at Their Gating Brake The Journal of Biological Chemistry. 12, 2017 | Pubmed ID: 28972185 Ca Regulation of Ca3.3 T-type Ca Channel Is Mediated by Calmodulin Molecular Pharmacology. 09, 2017 | Pubmed ID: 28696213 Nalcn Is a "Leak" Sodium Channel That Regulates Excitability of Brainstem Chemosensory Neurons and Breathing The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 08, 2016 | Pubmed ID: 27488637 Central Mechanisms Mediating Thrombospondin-4-induced Pain States The Journal of Biological Chemistry. Jun, 2016 | Pubmed ID: 27129212 Activation of Pyramidal Neurons in Mouse Medial Prefrontal Cortex Enhances Food-Seeking Behavior While Reducing Impulsivity in the Absence of an Effect on Food Intake Frontiers in Behavioral Neuroscience. 2016 | Pubmed ID: 27065827 Contrasting the Roles of the I-II Loop Gating Brake in CaV3.1 and CaV3.3 Calcium Channels Pflugers Archiv : European Journal of Physiology. Dec, 2015 | Pubmed ID: 26306541 CaV3.2 Calcium Channels Control NMDA Receptor-mediated Transmission: a New Mechanism for Absence Epilepsy Genes & Development. Jul, 2015 | Pubmed ID: 26220996 PHYSIOLOGY. Regulation of Breathing by CO₂ Requires the Proton-activated Receptor GPR4 in Retrotrapezoid Nucleus Neurons Science (New York, N.Y.). Jun, 2015 | Pubmed ID: 26068853 Ins and Outs of T-channel Structure Function Pflugers Archiv : European Journal of Physiology. Apr, 2014 | Pubmed ID: 24337909 A Potassium Leak Channel Silences Hyperactive Neurons and Ameliorates Status Epilepticus Epilepsia. Feb, 2014 | Pubmed ID: 24299204 Mechanisms by Which a CACNA1H Mutation in Epilepsy Patients Increases Seizure Susceptibility The Journal of Physiology. Feb, 2014 | Pubmed ID: 24277868 Effects of Eugenol on T-type Ca2+ Channel Isoforms The Journal of Pharmacology and Experimental Therapeutics. Nov, 2013 | Pubmed ID: 24014106 Molecular and Biophysical Basis of Glutamate and Trace Metal Modulation of Voltage-gated Ca(v)2.3 Calcium Channels The Journal of General Physiology. Mar, 2012 | Pubmed ID: 22371363 Enhanced Actions of Adenosine in Medial Entorhinal Cortex Layer II Stellate Neurons in Temporal Lobe Epilepsy Are Mediated Via A(1)-receptor Activation Epilepsia. Jan, 2012 | Pubmed ID: 22126400 The Voltage Dependence of Gating Currents of the Neuronal CA(v)3.3 Channel is Determined by the Gating Brake in the I-II Loop Pflugers Archiv : European Journal of Physiology. Apr, 2011 | Pubmed ID: 21340458 Characterization of the Gating Brake in the I-II Loop of CaV3 T-type Calcium Channels Channels (Austin, Tex.). Nov-Dec, 2010 | Pubmed ID: 21099341 T-type Ca(2+) Channel Modulation by Otilonium Bromide American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2010 | Pubmed ID: 20203058 Role of Voltage-gated Calcium Channels in Epilepsy Pflugers Archiv : European Journal of Physiology. Jul, 2010 | Pubmed ID: 20091047 Structural Determinants of the High Affinity Extracellular Zinc Binding Site on Cav3.2 T-type Calcium Channels The Journal of Biological Chemistry. Jan, 2010 | Pubmed ID: 19940152 Orientation of Palmitoylated CaVbeta2a Relative to CaV2.2 is Critical for Slow Pathway Modulation of N-type Ca2+ Current by Tachykinin Receptor Activation The Journal of General Physiology. Nov, 2009 | Pubmed ID: 19858358 Molecular Mechanisms of Lipoic Acid Modulation of T-type Calcium Channels in Pain Pathway The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2009 | Pubmed ID: 19641113 Molecular Pharmacology of Human Cav3.2 T-type Ca2+ Channels: Block by Antihypertensives, Antiarrhythmics, and Their Analogs The Journal of Pharmacology and Experimental Therapeutics. Feb, 2009 | Pubmed ID: 18974361 Orientation of the Calcium Channel Beta Relative to the Alpha(1)2.2 Subunit is Critical for Its Regulation of Channel Activity PloS One. 2008 | Pubmed ID: 18958281 Alternative Splicing Within the I-II Loop Controls Surface Expression of T-type Ca(v)3.1 Calcium Channels FEBS Letters. Nov, 2008 | Pubmed ID: 18930057 I-II Loop Structural Determinants in the Gating and Surface Expression of Low Voltage-activated Calcium Channels PloS One. Aug, 2008 | Pubmed ID: 18714336 Characterization of the Gating Brake in the I-II Loop of Ca(v)3.2 T-type Ca(2+) Channels The Journal of Biological Chemistry. Mar, 2008 | Pubmed ID: 18218623 Molecular Mechanisms of Subtype-specific Inhibition of Neuronal T-type Calcium Channels by Ascorbate The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2007 | Pubmed ID: 18003836 Reducing Agents Sensitize C-type Nociceptors by Relieving High-affinity Zinc Inhibition of T-type Calcium Channels The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2007 | Pubmed ID: 17670971 The I-II Loop Controls Plasma Membrane Expression and Gating of Ca(v)3.2 T-type Ca2+ Channels: a Paradigm for Childhood Absence Epilepsy Mutations The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2007 | Pubmed ID: 17215393 Molecular Biology of T-type Calcium Channels CNS & Neurological Disorders Drug Targets. Dec, 2006 | Pubmed ID: 17168745 Molecular Characterization of T-type Calcium Channels Cell Calcium. Aug, 2006 | Pubmed ID: 16759699 CaV3.2 is the Major Molecular Substrate for Redox Regulation of T-type Ca2+ Channels in the Rat and Mouse Thalamus The Journal of Physiology. Jul, 2006 | Pubmed ID: 16644797 The Endogenous Redox Agent L-cysteine Induces T-type Ca2+ Channel-dependent Sensitization of a Novel Subpopulation of Rat Peripheral Nociceptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005 | Pubmed ID: 16177046 Transfer of Beta Subunit Regulation from High to Low Voltage-gated Ca2+ Channels FEBS Letters. Jul, 2005 | Pubmed ID: 15987636 Functional Characterization and Neuronal Modeling of the Effects of Childhood Absence Epilepsy Variants of CACNA1H, a T-type Calcium Channel The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2005 | Pubmed ID: 15888660 Contrasting Anesthetic Sensitivities of T-type Ca2+ Channels of Reticular Thalamic Neurons and Recombinant Ca(v)3.3 Channels British Journal of Pharmacology. Jan, 2005 | Pubmed ID: 15644869 The Role of Voltage Gated T-type Ca2+ Channel Isoforms in Mediating "capacitative" Ca2+ Entry in Cancer Cells Cell Calcium. Dec, 2004 | Pubmed ID: 15488598 Functional Impact of Alternative Splicing of Human T-type Cav3.3 Calcium Channels Journal of Neurophysiology. Dec, 2004 | Pubmed ID: 15254077 Paradoxical Role of T-type Calcium Channels in Coronary Smooth Muscle Molecular Interventions. Feb, 2004 | Pubmed ID: 14993472 Cloning of a Novel One-repeat Calcium Channel-like Gene Biochemical and Biophysical Research Communications. Mar, 2003 | Pubmed ID: 12646162 Molecular Physiology of Low-voltage-activated T-type Calcium Channels Physiological Reviews. Jan, 2003 | Pubmed ID: 12506128 Alternative Splicing of the Rat Ca(v)3.3 T-type Calcium Channel Gene Produces Variants with Distinct Functional Properties(1) FEBS Letters. Sep, 2002 | Pubmed ID: 12297319 Cloning and Expression of the Human T-type Channel Ca(v)3.3: Insights into Prepulse Facilitation Biophysical Journal. Jul, 2002 | Pubmed ID: 12080115 Stimulation of Recombinant Ca(v)3.2, T-type, Ca(2+) Channel Currents by CaMKIIgamma(C) The Journal of Physiology. Jan, 2002 | Pubmed ID: 11790804 Gating Kinetics of the Alpha1I T-type Calcium Channel The Journal of General Physiology. Nov, 2001 | Pubmed ID: 11696605 Ducky Mouse Phenotype of Epilepsy and Ataxia is Associated with Mutations in the Cacna2d2 Gene and Decreased Calcium Channel Current in Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2001 | Pubmed ID: 11487633 Functional Properties of a New Voltage-dependent Calcium Channel Alpha(2)delta Auxiliary Subunit Gene (CACNA2D2) The Journal of Biological Chemistry. Apr, 2000 | Pubmed ID: 10766861 Differential Distribution of Three Members of a Gene Family Encoding Low Voltage-activated (T-type) Calcium Channels The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 1999 | Pubmed ID: 10066243 Low-voltage-activated Ca2+ Currents Are Generated by Members of the CavT Subunit Family (alpha1G/H) in Rat Primary Sensory Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1998 | Pubmed ID: 9786968 تحضير وزرع أقطاب كهربائية لفئران VGAT-cre المشتعلة كهربائيا لتوليد نموذج لصرع الفص الصدغي Justyna Straub1, Iuliia Vitko1, Ronald P. Gaykema1, Edward Perez-Reyes1,2 1Department of Pharmacology, University of Virginia, 2UVA Brain Institute, University of Virginia JoVE 62929 神经科学
تحضير وزرع أقطاب كهربائية لفئران VGAT-cre المشتعلة كهربائيا لتوليد نموذج لصرع الفص الصدغي Justyna Straub1, Iuliia Vitko1, Ronald P. Gaykema1, Edward Perez-Reyes1,2 1Department of Pharmacology, University of Virginia, 2UVA Brain Institute, University of Virginia JoVE 62929 神经科学