Eiji Shigetomi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Eiji Shigetomi has not added a biography. If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron. Aug, 2017 | Pubmed ID: 28712653 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Probing the Complexities of Astrocyte Calcium Signaling Trends in Cell Biology. Apr, 2016 | Pubmed ID: 26896246 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Imaging Calcium Microdomains Within Entire Astrocyte Territories and Endfeet with GCaMPs Expressed Using Adeno-associated Viruses The Journal of General Physiology. May, 2013 | Pubmed ID: 23589582 TRPA1 渠道调节星形胶质细胞静息钙及 GAT 3 通过抑制突触效能。 Nature Neuroscience. Jan, 2012 | Pubmed ID: 22158513 受体 P2X2 神经元是探索等离子膜激活时的移动 ATP 传感器。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22090499 [由星形胶质细胞的突触调节]。 Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Oct, 2011 | Pubmed ID: 21986065 钙指标染料,星形胶质细胞生理学研究大批量加载: 关键的限制和改善使用形态的地图。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21697385 监测与改进膜的星形胶质细胞钙微区针对 GCaMP 记者。 Neuron Glia Biology. Dec, 2010 | Pubmed ID: 21205365 基因有针对性的光学传感器监测钙信号在星形胶质细胞过程中。 Nature Neuroscience. Jun, 2010 | Pubmed ID: 20495558 两种形式的星形胶质细胞钙兴奋性锥体神经元中得到了显著的效果,对 NMDA 受体介导缓慢内向电流。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579739 跟踪变送器封闭 P2X 阳离子通道激活体外和体内。 Nature Methods. Jan, 2008 | Pubmed ID: 18084300 [在大脑突触嘌监管复杂]。 Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2007 | Pubmed ID: 17633523 便利的自发性甘氨酸释放的缺氧增强当前的大鼠舌下神经的运动神经元的 NMDA 受体。 The European Journal of Neuroscience. Mar, 2007 | Pubmed ID: 17408431 基础谷氨酸的阻滞剂抗突触前电压依赖性 Ca2 + 渠道释放在小鼠孤。 Brain Research. Aug, 2006 | Pubmed ID: 16814754 ATP 频率过滤的核孤束核内网络中所发挥双重作用。 Advances in Experimental Medicine and Biology. 2004 | Pubmed ID: 15602957 独立于动作电位的谷氨酸释放的 Ca2 + 进入突触前 P2X 受体通过诱发脑干自主网络中的突触后射击。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15044552 三磷酸腺苷和腺苷-介导中枢神经系统信号传导: 突触 Purinoceptors: ATP 可以发挥其"双重角色"的阶段。 Journal of Pharmacological Sciences. Feb, 2004 | Pubmed ID: 14978346 微分方程在大鼠迷走神经传出神经元后迷走神经节 P2X 受体水平增加。 Brain Research. Jul, 2003 | Pubmed ID: 12788520 分析控制的膜片钳记录脑干切片中的突触传递的分子机制。 Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2003 | Pubmed ID: 12777844 体内 使用大颅窗的小鼠宽场和双光子钙成像 Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 神经科学 通过非侵入性经鼻途径在免疫功能正常的小鼠大脑中移植人诱导的多能干细胞衍生小胶质细胞 Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 神经科学 近质膜和全球星形胶质细胞内钙动力学测量 Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 生物学
体内 使用大颅窗的小鼠宽场和双光子钙成像 Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 神经科学
通过非侵入性经鼻途径在免疫功能正常的小鼠大脑中移植人诱导的多能干细胞衍生小胶质细胞 Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 神经科学
近质膜和全球星形胶质细胞内钙动力学测量 Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 生物学