John H. Sampson Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery Duke University Biography Publications Institution JoVE Articles John H. Sampson has not added a biography. If you are John H. Sampson and would like to personalize this page please email our Author Liaison for assistance. Publications Proteomic Profiling of Patient-derived Glioblastoma Xenografts Identifies a Subset with Activated EGFR: Implications for Drug Development Journal of Neurochemistry. Jan, 2015 | Pubmed ID: 25598002 A Phase II, Multicenter Trial of Rindopepimut (CDX-110) in Newly Diagnosed Glioblastoma: the ACT III Study Neuro-oncology. Jan, 2015 | Pubmed ID: 25586468 Increased Proportion of FoxP3+ Regulatory T Cells in Tumor Infiltrating Lymphocytes is Associated with Tumor Recurrence and Reduced Survival in Patients with Glioblastoma Cancer Immunology, Immunotherapy : CII. Jan, 2015 | Pubmed ID: 25555571 Enhancing Dendritic Cell-based Vaccination for Highly Aggressive Glioblastoma Expert Opinion on Biological Therapy. Jan, 2015 | Pubmed ID: 25327832 Chimeric Antigen Receptor Engineered T Cells Can Eliminate Brain Tumors and Initiate Long-term Protection Against Recurrence Oncoimmunology. 2014 | Pubmed ID: 25610729 Leveraging Chemotherapy-induced Lymphopenia to Potentiate Cancer Immunotherapy Oncoimmunology. 2014 | Pubmed ID: 25610727 Peptide Vaccines for the Treatment of Glioblastoma Journal of Neuro-oncology. Dec, 2014 | Pubmed ID: 25491947 Defining the Optimal Planning Target Volume in Image-Guided Stereotactic Radiosurgery of Brain Metastases: Results of a Randomized Trial International Journal of Radiation Oncology, Biology, Physics. Oct, 2014 | Pubmed ID: 25442342 Immunotherapy for Primary Brain Tumors: No Longer a Matter of Privilege Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2014 | Pubmed ID: 25398845 Severe Adverse Immunologic Reaction in a Patient with Glioblastoma Receiving Autologous Dendritic Cell Vaccines Combined with GM-CSF and Dose-Intensified Temozolomide Cancer Immunology Research. Nov, 2014 | Pubmed ID: 25387895 Targeting MiR-23a in CD8+ Cytotoxic T Lymphocytes Prevents Tumor-dependent Immunosuppression The Journal of Clinical Investigation. Dec, 2014 | Pubmed ID: 25347474 Epidermal Growth Factor Receptor and Variant III Targeted Immunotherapy Neuro-oncology. Oct, 2014 | Pubmed ID: 25342601 Recurrent Malignant Gliomas Seminars in Radiation Oncology. Oct, 2014 | Pubmed ID: 25219814 Immunotherapy Advances for Glioblastoma Neuro-oncology. Nov, 2014 | Pubmed ID: 25190673 Rindopepimut: a Promising Immunotherapeutic for the Treatment of Glioblastoma Multiforme Immunotherapy. Jun, 2014 | Pubmed ID: 25186601 Antibody-based Immunotherapy for Malignant Glioma Seminars in Oncology. Aug, 2014 | Pubmed ID: 25173142 Standard of Care and Future Pharmacological Treatment Options for Malignant Glioma: an Urgent Need for Screening and Identification of Novel Tumor-specific Antigens Expert Opinion on Pharmacotherapy. Oct, 2014 | Pubmed ID: 25139628 Immunological Targeting of Cytomegalovirus for Glioblastoma Therapy Oncoimmunology. 2014 | Pubmed ID: 25101224 A Novel, Reproducible, and Objective Method for Volumetric Magnetic Resonance Imaging Assessment of Enhancing Glioblastoma Journal of Neurosurgery. Sep, 2014 | Pubmed ID: 25036205 Oncolytic Polio Virotherapy of Cancer Cancer. Nov, 2014 | Pubmed ID: 24939611 Worse Outcomes for Patients Undergoing Brain Tumor and Cerebrovascular Procedures Following the ACGME Resident Duty-hour Restrictions Journal of Neurosurgery. Aug, 2014 | Pubmed ID: 24926647 Response Journal of Neurosurgery. Mar, 2014 | Pubmed ID: 24724172 EGFRvIII-specific Chimeric Antigen Receptor T Cells Migrate to and Kill Tumor Deposits Infiltrating the Brain Parenchyma in an Invasive Xenograft Model of Glioblastoma PloS One. 2014 | Pubmed ID: 24722266 Recognition and Killing of Autologous, Primary Glioblastoma Tumor Cells by Human Cytomegalovirus Pp65-specific Cytotoxic T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2014 | Pubmed ID: 24658154 Methodology and Reporting of Meta-analyses in the Neurosurgical Literature Journal of Neurosurgery. Apr, 2014 | Pubmed ID: 24460491 Editorial on "heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccination for Recurrent Glioblastoma: a Phase II, Single Arm Trial" Neuro-oncology. Jan, 2014 | Pubmed ID: 24443362 Impact of PhD Training on Scholarship in a Neurosurgical Career Journal of Neurosurgery. Mar, 2014 | Pubmed ID: 24359004 EGFRvIII MCAR-modified T-cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity Against Tumor-antigen Loss Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2014 | Pubmed ID: 24352643 SEER Insights Journal of Neurosurgery. Feb, 2014 | Pubmed ID: 24286150 Intracerebral Delivery of a Third Generation EGFRvIII-specific Chimeric Antigen Receptor is Efficacious Against Human Glioma Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Jan, 2014 | Pubmed ID: 24054399 Human Regulatory T Cells Kill Tumor Cells Through Granzyme-dependent Cytotoxicity Upon Retargeting with a Bispecific Antibody Cancer Immunology Research. Sep, 2013 | Pubmed ID: 24570975 Regulatory T Cells Are Redirected to Kill Glioblastoma by an EGFRvIII-targeted Bispecific Antibody Oncoimmunology. Dec, 2013 | Pubmed ID: 24475376 Enhanced Oncolytic Virotherapy Through Oxidative Stress Inhibition Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2013 | Pubmed ID: 24201213 A Cytokine Cocktail Directly Modulates the Phenotype of DC-enriched Anti-tumor T Cells to Convey Potent Anti-tumor Activities in a Murine Model Cancer Immunology, Immunotherapy : CII. Nov, 2013 | Pubmed ID: 23982483 An EGFRvIII-targeted Bispecific T-cell Engager Overcomes Limitations of the Standard of Care for Glioblastoma Expert Review of Clinical Pharmacology. Jul, 2013 | Pubmed ID: 23927666 Antibody, T-cell and Dendritic Cell Immunotherapy for Malignant Brain Tumors Future Oncology (London, England). Jul, 2013 | Pubmed ID: 23837761 Rational Design and Generation of Recombinant Control Reagents for Bispecific Antibodies Through CDR Mutagenesis Journal of Immunological Methods. Sep, 2013 | Pubmed ID: 23806556 Complete Response to Steroids in Dural Inflammatory Pseudotumor Associated with Still's Disease Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Oct, 2013 | Pubmed ID: 23768965 An Update on Vaccine Therapy and Other Immunotherapeutic Approaches for Glioblastoma Expert Review of Vaccines. Jun, 2013 | Pubmed ID: 23750791 A Novel Bispecific Antibody Recruits T Cells to Eradicate Tumors in the "immunologically Privileged" Central Nervous System Oncoimmunology. Apr, 2013 | Pubmed ID: 23734318 Concurrent Stereotactic Radiosurgery and Bevacizumab in Recurrent Malignant Gliomas: a Prospective Trial International Journal of Radiation Oncology, Biology, Physics. Aug, 2013 | Pubmed ID: 23725997 Clinicopathological Characteristics and Treatment of Rhabdoid Glioblastoma Journal of Neurosurgery. Aug, 2013 | Pubmed ID: 23641829 Radiotherapy and Radiosurgery for Tumors of the Central Nervous System Surgical Oncology Clinics of North America. Jul, 2013 | Pubmed ID: 23622073 BLyS Levels Correlate with Vaccine-induced Antibody Titers in Patients with Glioblastoma Lymphodepleted by Therapeutic Temozolomide Cancer Immunology, Immunotherapy : CII. Jun, 2013 | Pubmed ID: 23591978 Isocitrate Dehydrogenase 1: What It Means to the Neurosurgeon: a Review Journal of Neurosurgery. Jun, 2013 | Pubmed ID: 23581583 Myeloablative Temozolomide Enhances CD8⁺ T-cell Responses to Vaccine and is Required for Efficacy Against Brain Tumors in Mice PloS One. 2013 | Pubmed ID: 23527092 Thickness of Subcutaneous Fat As a Risk Factor for Infection in Cervical Spine Fusion Surgery The Journal of Bone and Joint Surgery. American Volume. Feb, 2013 | Pubmed ID: 23426766 Systemic Administration of a Bispecific Antibody Targeting EGFRvIII Successfully Treats Intracerebral Glioma Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23248284 Subarachnoid Hemorrhage Trials Journal of Neurosurgery. Jan, 2013 | Pubmed ID: 23039153 Contemporary Surgical Management of Vestibular Schwannomas: Analysis of Complications and Lessons Learned over the Past Decade Neurosurgery. Jun, 2013 | Pubmed ID: 23037828 Therapeutic Approaches for HER2-positive Brain Metastases: Circumventing the Blood-brain Barrier Cancer Treatment Reviews. May, 2013 | Pubmed ID: 22727691 The Limitations of Imaging Response Criteria The Lancet. Oncology. Nov, 2012 | Pubmed ID: 23116995 Regulatory T Cells Move in when Gliomas Say "I Do" Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2012 | Pubmed ID: 23052252 Enzyme Redesign Guided by Cancer-derived IDH1 Mutations Nature Chemical Biology. Nov, 2012 | Pubmed ID: 23001033 Editorial: Convection-enhanced Delivery Journal of Neurosurgery. Dec, 2012 | Pubmed ID: 22998062 Stereotactic Radiosurgery and Bevacizumab for Recurrent Glioblastoma Multiforme Journal of the National Comprehensive Cancer Network : JNCCN. Jun, 2012 | Pubmed ID: 22679114 The Use of Motor Mapping to Aid Resection of Eloquent Gliomas Neurosurgery Clinics of North America. Apr, 2012 | Pubmed ID: 22440865 Resection and Survival Journal of Neurosurgery. Jun, 2012 | Pubmed ID: 22424561 Phase 1 Trial of Dasatinib Plus Erlotinib in Adults with Recurrent Malignant Glioma Journal of Neuro-oncology. Jul, 2012 | Pubmed ID: 22407177 Toxin-based Targeted Therapy for Malignant Brain Tumors Clinical & Developmental Immunology. 2012 | Pubmed ID: 22400035 A Pilot Study of IL-2Rα Blockade During Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with Glioblastoma PloS One. 2012 | Pubmed ID: 22383993 Convection Enhanced Delivery of Macromolecules for Brain Tumors Current Drug Discovery Technologies. Dec, 2012 | Pubmed ID: 22339074 Immunotherapy with Tumor Vaccines for the Treatment of Malignant Gliomas Current Drug Discovery Technologies. Dec, 2012 | Pubmed ID: 22339070 Clinical Data Simplified Journal of Neurosurgery. Feb, 2012 | Pubmed ID: 22054209 Avastin: More Questions Than Answers. . Journal of Neurosurgery. Feb, 2012 | Pubmed ID: 22035270 Phase II Study of Carboplatin, Irinotecan, and Bevacizumab for Bevacizumab Naïve, Recurrent Glioblastoma Journal of Neuro-oncology. Mar, 2012 | Pubmed ID: 21986722 Phase II Study of Gleevec® Plus Hydroxyurea (HU) in Adults with Progressive or Recurrent Meningioma Journal of Neuro-oncology. Jan, 2012 | Pubmed ID: 21938530 Disparities in Care Journal of Neurosurgery. Feb, 2012 | Pubmed ID: 21740120 Application of Novel Response/progression Measures for Surgically Delivered Therapies for Gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group Neurosurgery. Jan, 2012 | Pubmed ID: 21593697 Safety and Efficacy of Stereotactic Radiosurgery and Adjuvant Bevacizumab in Patients with Recurrent Malignant Gliomas International Journal of Radiation Oncology, Biology, Physics. Apr, 2012 | Pubmed ID: 21489708 Imaging of Convection Enhanced Delivery of Toxins in Humans Toxins. Mar, 2011 | Pubmed ID: 22069706 Monitoring Radiographic Brain Tumor Progression Toxins. Mar, 2011 | Pubmed ID: 22069705 Bevacizumab-induced Reversible Posterior Leukoencephalopathy Syndrome and Successful Retreatment in a Patient with Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2011 | Pubmed ID: 21900098 Monoclonal Antibody Blockade of IL-2 Receptor α During Lymphopenia Selectively Depletes Regulatory T Cells in Mice and Humans Blood. Sep, 2011 | Pubmed ID: 21768296 Is Cytomegalovirus a Therapeutic Target in Glioblastoma? Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2011 | Pubmed ID: 21632859 Convection-enhanced Delivery Journal of Neurosurgery. Sep, 2011 | Pubmed ID: 21619413 Phase 2 Study of Carboplatin, Irinotecan, and Bevacizumab for Recurrent Glioblastoma After Progression on Bevacizumab Therapy Cancer. Dec, 2011 | Pubmed ID: 21590689 Our Failure to Advance New Treatments for Glioma to Market Journal of Neurosurgery. Aug, 2011 | Pubmed ID: 21568655 The Addition of Bevacizumab to Standard Radiation Therapy and Temozolomide Followed by Bevacizumab, Temozolomide, and Irinotecan for Newly Diagnosed Glioblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2011 | Pubmed ID: 21531816 Epidemiology Journal of Neurosurgery. Aug, 2011 | Pubmed ID: 21529133 A Review of VEGF/VEGFR-targeted Therapeutics for Recurrent Glioblastoma Journal of the National Comprehensive Cancer Network : JNCCN. Apr, 2011 | Pubmed ID: 21464146 Bispecific Antibodies Engage T Cells for Antitumor Immunotherapy Expert Opinion on Biological Therapy. Jul, 2011 | Pubmed ID: 21449821 Colocalization of Gadolinium-diethylene Triamine Pentaacetic Acid with High-molecular-weight Molecules After Intracerebral Convection-enhanced Delivery in Humans Neurosurgery. Sep, 2011 | Pubmed ID: 21430586 Clinical Trial End Points for High-grade Glioma: the Evolving Landscape Neuro-oncology. Mar, 2011 | Pubmed ID: 21310734 A Novel Method for Volumetric MRI Response Assessment of Enhancing Brain Tumors PloS One. 2011 | Pubmed ID: 21298088 Resection of Vestibular Schwannomas Journal of Neurosurgery. May, 2011 | Pubmed ID: 21250806 Greater Chemotherapy-induced Lymphopenia Enhances Tumor-specific Immune Responses That Eliminate EGFRvIII-expressing Tumor Cells in Patients with Glioblastoma Neuro-oncology. Mar, 2011 | Pubmed ID: 21149254 Immunotherapy Coming of Age: What Will It Take to Make It Standard of Care for Glioblastoma? Neuro-oncology. Jan, 2011 | Pubmed ID: 21149252 A Comprehensive Outlook on Intracerebral Therapy of Malignant Gliomas Critical Reviews in Oncology/hematology. Oct, 2011 | Pubmed ID: 20888252 Low-grade Glioma Journal of Neurosurgery. Mar, 2011 | Pubmed ID: 20635855 Effect of Imaging and Catheter Characteristics on Clinical Outcome for Patients in the PRECISE Study Journal of Neuro-oncology. Jan, 2011 | Pubmed ID: 20563833 Effect of CYP3A-inducing Anti-epileptics on Sorafenib Exposure: Results of a Phase II Study of Sorafenib Plus Daily Temozolomide in Adults with Recurrent Glioblastoma Journal of Neuro-oncology. Jan, 2011 | Pubmed ID: 20443129 Immunologic Escape After Prolonged Progression-free Survival with Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients with Newly Diagnosed Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2010 | Pubmed ID: 20921459 Stereotactic Radiosurgery in the Treatment of a Dural Carotid-cavernous Fistula Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. Jun, 2010 | Pubmed ID: 20431489 Immunotherapy Approaches for Malignant Glioma from 2007 to 2009 Current Neurology and Neuroscience Reports. Jul, 2010 | Pubmed ID: 20424975 Long-term Safety of Combined Intracerebral Delivery of Free Gadolinium and Targeted Chemotherapeutic Agent PRX321 Neurological Research. Oct, 2010 | Pubmed ID: 20021739 Poor Drug Distribution As a Possible Explanation for the Results of the PRECISE Trial Journal of Neurosurgery. Aug, 2010 | Pubmed ID: 20020841 Bevacizumab Fails to Treat Temporal Paraganglioma: Discussion and Case Illustration Journal of Neuro-oncology. Jul, 2010 | Pubmed ID: 20020179 The Role of Tregs in Glioma-mediated Immunosuppression: Potential Target for Intervention Neurosurgery Clinics of North America. Jan, 2010 | Pubmed ID: 19944972 Clinical Applications of a Peptide-based Vaccine for Glioblastoma Neurosurgery Clinics of North America. Jan, 2010 | Pubmed ID: 19944970 Convection-enhanced Delivery of Free Gadolinium with the Recombinant Immunotoxin MR1-1 Journal of Neuro-oncology. May, 2010 | Pubmed ID: 19898744 Phase 2 Trial of Erlotinib Plus Sirolimus in Adults with Recurrent Glioblastoma Journal of Neuro-oncology. Jan, 2010 | Pubmed ID: 19562254 The Role of Tregs in Human Glioma Patients and Their Inhibition with a Novel STAT-3 Inhibitor Clinical Neurosurgery. 2009 | Pubmed ID: 20214040 An Epidermal Growth Factor Receptor Variant III-targeted Vaccine is Safe and Immunogenic in Patients with Glioblastoma Multiforme Molecular Cancer Therapeutics. Oct, 2009 | Pubmed ID: 19825799 EGFRvIII-targeted Vaccination Therapy of Malignant Glioma Brain Pathology (Zurich, Switzerland). Oct, 2009 | Pubmed ID: 19744042 Treatment of HER2-positive Breast Carcinomatous Meningitis with Intrathecal Administration of Alpha-particle-emitting (211)At-labeled Trastuzumab Nuclear Medicine and Biology. Aug, 2009 | Pubmed ID: 19647172 The PEPvIII-KLH (CDX-110) Vaccine in Glioblastoma Multiforme Patients Expert Opinion on Biological Therapy. Aug, 2009 | Pubmed ID: 19591631 Toward Effective Immunotherapy for the Treatment of Malignant Brain Tumors Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jul, 2009 | Pubmed ID: 19560742 Phase II Trial of Temozolomide (TMZ) Plus Irinotecan (CPT-11) in Adults with Newly Diagnosed Glioblastoma Multiforme Before Radiotherapy Journal of Neuro-oncology. Dec, 2009 | Pubmed ID: 19533023 A Constitutively Active Form of Neurokinin 1 Receptor and Neurokinin 1 Receptor-mediated Apoptosis in Glioblastomas Journal of Neurochemistry. May, 2009 | Pubmed ID: 19519779 Paraganglioma of the Head and Neck: Long-term Local Control with Radiotherapy American Journal of Clinical Oncology. Jun, 2009 | Pubmed ID: 19433962 IgE, Allergy, and Risk of Glioma: Update from the San Francisco Bay Area Adult Glioma Study in the Temozolomide Era International Journal of Cancer. Journal International Du Cancer. Aug, 2009 | Pubmed ID: 19408307 Phase 1 Trial of Temozolomide Plus Irinotecan Plus O6-benzylguanine in Adults with Recurrent Malignant Glioma Cancer. Jul, 2009 | Pubmed ID: 19402172 Phase I Trial of Temozolomide Plus O6-benzylguanine 5-day Regimen with Recurrent Malignant Glioma Neuro-oncology. Oct, 2009 | Pubmed ID: 19289491 Phase II Trial of Temozolomide Plus O6-benzylguanine in Adults with Recurrent, Temozolomide-resistant Malignant Glioma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2009 | Pubmed ID: 19204199 Phase II Trial of Gliadel Plus O6-benzylguanine in Adults with Recurrent Glioblastoma Multiforme Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2009 | Pubmed ID: 19188181 Proteomic and Immunologic Analyses of Brain Tumor Exosomes FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2009 | Pubmed ID: 19109410 Stereotactic Body Radiotherapy for Lesions of the Spine and Paraspinal Regions International Journal of Radiation Oncology, Biology, Physics. Apr, 2009 | Pubmed ID: 19004569 A Novel Inhibitor of Signal Transducers and Activators of Transcription 3 Activation is Efficacious Against Established Central Nervous System Melanoma and Inhibits Regulatory T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2008 | Pubmed ID: 18794085 Detection of Humoral Response in Patients with Glioblastoma Receiving EGFRvIII-KLH Vaccines Journal of Immunological Methods. Nov, 2008 | Pubmed ID: 18775433 Tumor-specific Immunotherapy Targeting the EGFRvIII Mutation in Patients with Malignant Glioma Seminars in Immunology. Oct, 2008 | Pubmed ID: 18539480 Combating Immunosuppression in Glioma Future Oncology (London, England). Jun, 2008 | Pubmed ID: 18518768 Immunotherapy Against Angiogenesis-associated Targets: Evidence and Implications for the Treatment of Malignant Glioma Expert Review of Anticancer Therapy. May, 2008 | Pubmed ID: 18471045 Selective Modification of Antigen-specific T Cells by RNA Electroporation Human Gene Therapy. May, 2008 | Pubmed ID: 18471037 Intracerebral Infusion of an EGFR-targeted Toxin in Recurrent Malignant Brain Tumors Neuro-oncology. Jun, 2008 | Pubmed ID: 18403491 Cryptococcal Meningitis in Patients with Glioma: a Report of Two Cases Journal of Neuro-oncology. Aug, 2008 | Pubmed ID: 18398572 Immunotherapy of Malignant Brain Tumors Immunological Reviews. Apr, 2008 | Pubmed ID: 18363995 Cholesterol Granuloma of the Lateral Ventricle. Case Report Journal of Neurosurgery. Feb, 2008 | Pubmed ID: 18240934 Immunological Responses in a Patient with Glioblastoma Multiforme Treated with Sequential Courses of Temozolomide and Immunotherapy: Case Study Neuro-oncology. Feb, 2008 | Pubmed ID: 18079360 Sensitive Detection of Human Cytomegalovirus in Tumors and Peripheral Blood of Patients Diagnosed with Glioblastoma Neuro-oncology. Feb, 2008 | Pubmed ID: 17951512 EGFRvIII-targeted Immunotoxin Induces Antitumor Immunity That is Inhibited in the Absence of CD4+ and CD8+ T Cells Cancer Immunology, Immunotherapy : CII. Jan, 2008 | Pubmed ID: 17634939 Convection-enhanced Delivery of Cintredekin Besudotox (interleukin-13-PE38QQR) Followed by Radiation Therapy with and Without Temozolomide in Newly Diagnosed Malignant Gliomas: Phase 1 Study of Final Safety Results Neurosurgery. Nov, 2007 | Pubmed ID: 18091279 Clinical Utility of a Patient-specific Algorithm for Simulating Intracerebral Drug Infusions Neuro-oncology. Jul, 2007 | Pubmed ID: 17435179 Viruses in the Treatment of Malignant Glioma Expert Review of Neurotherapeutics. Apr, 2007 | Pubmed ID: 17425484 Systemic CTLA-4 Blockade Ameliorates Glioma-induced Changes to the CD4+ T Cell Compartment Without Affecting Regulatory T-cell Function Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007 | Pubmed ID: 17404100 Direct Intracerebral Delivery of Cintredekin Besudotox (IL13-PE38QQR) in Recurrent Malignant Glioma: a Report by the Cintredekin Besudotox Intraparenchymal Study Group Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2007 | Pubmed ID: 17327604 Induction of Hyperintense Signal on T2-weighted MR Images Correlates with Infusion Distribution from Intracerebral Convection-enhanced Delivery of a Tumor-targeted Cytotoxin AJR. American Journal of Roentgenology. Mar, 2007 | Pubmed ID: 17312057 Intracerebral Infusate Distribution by Convection-enhanced Delivery in Humans with Malignant Gliomas: Descriptive Effects of Target Anatomy and Catheter Positioning Neurosurgery. Feb, 2007 | Pubmed ID: 17297371 Phase II Study of Imatinib Mesylate and Hydroxyurea for Recurrent Grade III Malignant Gliomas Journal of Neuro-oncology. May, 2007 | Pubmed ID: 17245623 Genetic Analysis of Intracranial Tumors in a Murine Model of Glioma Demonstrate a Shift in Gene Expression in Response to Host Immunity Journal of Neuroimmunology. Jan, 2007 | Pubmed ID: 17137636 Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T Cells in Patients with Malignant Glioma Reveals Differential Expression of the Immunologic Transcriptome Compared with T Cells from Healthy Volunteers Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2006 | Pubmed ID: 17189402 Treatment of Neoplastic Meningitis with Intrathecal 9-nitro-camptothecin Neurologia Medico-chirurgica. Oct, 2006 | Pubmed ID: 17062987 Preoperative Functional MR Imaging Localization of Language and Motor Areas: Effect on Therapeutic Decision Making in Patients with Potentially Resectable Brain Tumors Radiology. Sep, 2006 | Pubmed ID: 16857981 Systemic Anti-CD25 Monoclonal Antibody Administration Safely Enhances Immunity in Murine Glioma Without Eliminating Regulatory T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2006 | Pubmed ID: 16857805 Novel Human IgG2b/murine Chimeric Antitenascin Monoclonal Antibody Construct Radiolabeled with 131I and Administered into the Surgically Created Resection Cavity of Patients with Malignant Glioma: Phase I Trial Results Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2006 | Pubmed ID: 16741299 Safety of Intraparenchymal Convection-enhanced Delivery of Cintredekin Besudotox in Early-phase Studies Neurosurgical Focus. 2006 | Pubmed ID: 16709020 Comparison of Intratumoral Bolus Injection and Convection-enhanced Delivery of Radiolabeled Antitenascin Monoclonal Antibodies Neurosurgical Focus. 2006 | Pubmed ID: 16709019 Convection-enhanced Delivery of Therapeutics for Brain Disease, and Its Optimization Neurosurgical Focus. 2006 | Pubmed ID: 16709017 Increased Regulatory T-cell Fraction Amidst a Diminished CD4 Compartment Explains Cellular Immune Defects in Patients with Malignant Glioma Cancer Research. Mar, 2006 | Pubmed ID: 16540683 Targeted Therapy for Glioblastoma Multiforme Neoplastic Meningitis with Intrathecal Delivery of an Oncolytic Recombinant Poliovirus Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2006 | Pubmed ID: 16489093 Phase 1 Trial of Gefitinib Plus Sirolimus in Adults with Recurrent Malignant Glioma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2006 | Pubmed ID: 16467100 Phase II Study of Imatinib Mesylate Plus Hydroxyurea in Adults with Recurrent Glioblastoma Multiforme Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2005 | Pubmed ID: 16361636 Phase I Trial of Temozolomide Plus O6-benzylguanine for Patients with Recurrent or Progressive Malignant Glioma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2005 | Pubmed ID: 16192602 Surgical Management of Petroclival Meningiomas: Defining Resection Goals Based on Risk of Neurological Morbidity and Tumor Recurrence Rates in 137 Patients Neurosurgery. Mar, 2005 | Pubmed ID: 15730581 Sustained Radiographic and Clinical Response in Patient with Bifrontal Recurrent Glioblastoma Multiforme with Intracerebral Infusion of the Recombinant Targeted Toxin TP-38: Case Study Neuro-oncology. Jan, 2005 | Pubmed ID: 15701286 Poliovirus Receptor CD155-targeted Oncolysis of Glioma Neuro-oncology. Jul, 2004 | Pubmed ID: 15279713 Treatment of Intracerebral Neoplasia and Neoplastic Meningitis with Regional Delivery of Oncolytic Recombinant Poliovirus Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2004 | Pubmed ID: 15269159 Phase 1 Trial of Irinotecan Plus BCNU in Patients with Progressive or Recurrent Malignant Glioma Neuro-oncology. Apr, 2004 | Pubmed ID: 15134629 Phase 2 Trial of BCNU Plus Irinotecan in Adults with Malignant Glioma Neuro-oncology. Apr, 2004 | Pubmed ID: 15134628 Resistance to Tyrosine Kinase Inhibition by Mutant Epidermal Growth Factor Receptor Variant III Contributes to the Neoplastic Phenotype of Glioblastoma Multiforme Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2004 | Pubmed ID: 15131063 Microvascular Decompression for Glossopharyngeal Neuralgia: Long-term Effectiveness and Complication Avoidance Neurosurgery. Apr, 2004 | Pubmed ID: 15046654 Immunotherapy of Surgical Malignancies Current Problems in Surgery. Jan, 2004 | Pubmed ID: 14749625 Phase II Trial of Gefitinib in Recurrent Glioblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2004 | Pubmed ID: 14638850 Efficacy of Intracerebral Microinfusion of Trastuzumab in an Athymic Rat Model of Intracerebral Metastatic Breast Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2003 | Pubmed ID: 14654531 Progress Report of a Phase I Study of the Intracerebral Microinfusion of a Recombinant Chimeric Protein Composed of Transforming Growth Factor (TGF)-alpha and a Mutated Form of the Pseudomonas Exotoxin Termed PE-38 (TP-38) for the Treatment of Malignant Brain Tumors Journal of Neuro-oncology. Oct, 2003 | Pubmed ID: 14649883 Epidermal Growth Factor Receptor VIII Peptide Vaccination is Efficacious Against Established Intracerebral Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003 | Pubmed ID: 14519652 Adoptive Immunotherapy for Malignant Glioma Cancer Journal (Sudbury, Mass.). May-Jun, 2003 | Pubmed ID: 12952301 The History, Evolution, and Clinical Use of Dendritic Cell-based Immunization Strategies in the Therapy of Brain Tumors Journal of Neuro-oncology. Aug-Sep, 2003 | Pubmed ID: 12952297 Phase II Trial of Temozolomide in Patients with Progressive Low-grade Glioma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2003 | Pubmed ID: 12586801 Clinical Immunotherapy for Brain Tumors Neuroimaging Clinics of North America. Nov, 2002 | Pubmed ID: 12687917 Viruses in the Treatment of Brain Tumors Neuroimaging Clinics of North America. Nov, 2002 | Pubmed ID: 12687911 Brain Tumors in Mice Are Susceptible to Blockade of Epidermal Growth Factor Receptor (EGFR) with the Oral, Specific, EGFR-tyrosine Kinase Inhibitor ZD1839 (iressa) Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2002 | Pubmed ID: 12429640 Intracanalicular Meningioma Mimicking Vestibular Schwannoma AJNR. American Journal of Neuroradiology. Oct, 2002 | Pubmed ID: 12372737 Mutant Epidermal Growth Factor Receptor Up-regulates Molecular Effectors of Tumor Invasion Cancer Research. Jun, 2002 | Pubmed ID: 12067969 Phase II Trial of Carmustine Plus O(6)-benzylguanine for Patients with Nitrosourea-resistant Recurrent or Progressive Malignant Glioma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2002 | Pubmed ID: 11980998 Phase II Trial of Murine (131)I-labeled Antitenascin Monoclonal Antibody 81C6 Administered into Surgically Created Resection Cavities of Patients with Newly Diagnosed Malignant Gliomas Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2002 | Pubmed ID: 11870184 Generation of Anti-idiotypic Reagents in the EGFRvIII Tumor-associated Antigen System Cancer Immunology, Immunotherapy : CII. Feb, 2002 | Pubmed ID: 11862416 Dendritic Cells Pulsed with a Tumor-specific Peptide Induce Long-lasting Immunity and Are Effective Against Murine Intracerebral Melanoma Neurosurgery. Jan, 2002 | Pubmed ID: 11844246 Генерация CAR Т-клеток в усыновители терапии в контексте глиобластомы стандарт медицинской помощи Katherine Riccione1,2, Carter M. Suryadevara1,3, David Snyder1, Xiuyu Cui1, John H. Sampson1,2,3, Luis Sanchez-Perez1 1Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University, 2Department of Biomedical Engineering, Duke University, 3Department of Pathology, Duke University 免疫与感染
Генерация CAR Т-клеток в усыновители терапии в контексте глиобластомы стандарт медицинской помощи Katherine Riccione1,2, Carter M. Suryadevara1,3, David Snyder1, Xiuyu Cui1, John H. Sampson1,2,3, Luis Sanchez-Perez1 1Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University, 2Department of Biomedical Engineering, Duke University, 3Department of Pathology, Duke University 免疫与感染
