Sridhar Sivasubbu CSIR-Institute of Genomics and Integrative Biology Biography Publications Institution JoVE Articles Sridhar Sivasubbu has not added a biography. If you are Sridhar Sivasubbu and would like to personalize this page please email our Author Liaison for assistance. Publications An Insertion Map of the Indian Population: Identification and Analysis in 1021 Genomes of the IndiGen Project NAR Genomics and Bioinformatics. Mar, 2022 | Pubmed ID: 35178516 Clinical, Immunological and Genomic Characteristics of Children with X-linked Agammaglobulinemia from Kerala, South India Human Immunology. Jan, 2022 | Pubmed ID: 35074268 Variants of Concern Responsible for SARS-CoV-2 Vaccine Breakthrough Infections from India Journal of Medical Virology. 04, 2022 | Pubmed ID: 34786733 Genetic Epidemiology of Autoinflammatory Disease Variants in Indian Population from 1029 Whole Genomes Journal, Genetic Engineering & Biotechnology. Dec, 2021 | Pubmed ID: 34905135 SARS-CoV-2 Vaccine Breakthrough Infection Following a Previous Infection in a Healthcare Worker The Journal of Infection. Oct, 2021 | Pubmed ID: 34678389 Genomic Characterization and Epidemiology of an Emerging SARS-CoV-2 Variant in Delhi, India Science (New York, N.Y.). 11, 2021 | Pubmed ID: 34648303 A Genome-wide Circular RNA Transcriptome in Rat Biology Methods & Protocols. 2021 | Pubmed ID: 34527809 An Optimized, Amplicon-based Approach for Sequencing of SARS-CoV-2 from Patient Samples Using COVIDSeq Assay on Illumina MiSeq Sequencing Platforms STAR Protocols. 09, 2021 | Pubmed ID: 34368787 Whole Genome Sequencing Identifies Novel Structural Variant in a Large Indian Family Affected with X-linked Agammaglobulinemia PloS One. 2021 | Pubmed ID: 34252140 LncRNA VEAL2 Regulates PRKCB2 to Modulate Endothelial Permeability in Diabetic Retinopathy The EMBO Journal. 08, 2021 | Pubmed ID: 34180064 Genomic Survey of SARS-CoV-2 Vaccine Breakthrough Infections in Healthcare Workers from Kerala, India The Journal of Infection. 08, 2021 | Pubmed ID: 34044037 Genome and Transcriptome Analysis of the Mealybug Maconellicoccus Hirsutus: Correlation with Its Unique Phenotypes Genomics. 07, 2021 | Pubmed ID: 34022346 Symptomatic Reinfection of SARS-CoV-2 with Spike Protein Variant N440K Associated with Immune Escape Journal of Medical Virology. 07, 2021 | Pubmed ID: 33818797 High Throughput Detection and Genetic Epidemiology of SARS-CoV-2 Using COVIDSeq Next-generation Sequencing PloS One. 2021 | Pubmed ID: 33596239 Chronic Systemic Exposure to IL6 Leads to Deregulation of Glycolysis and Fat Accumulation in the Zebrafish Liver Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 05, 2021 | Pubmed ID: 33582286 Genomic Analysis of Patients in a South Indian Community with Autosomal Dominant Cortical Tremor, Myoclonus and Epilepsy Suggests a Founder Repeat Expansion Mutation in the Gene Brain Communications. 2021 | Pubmed ID: 33501421 DALIA- a Comprehensive Resource of Disease Alleles in Arab Population PloS One. 2021 | Pubmed ID: 33439861 Asymptomatic Reactivation of SARS-CoV-2 in a Child with Neuroblastoma Characterised by Whole Genome Sequencing IDCases. 2021 | Pubmed ID: 33288996 Analysis of the Potential Impact of Genomic Variants in Global SARS-CoV-2 Genomes on Molecular Diagnostic Assays International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Jan, 2021 | Pubmed ID: 33181329 IndiGenomes: a Comprehensive Resource of Genetic Variants from over 1000 Indian Genomes Nucleic Acids Research. 01, 2021 | Pubmed ID: 33095885 Parental Experience of Hematopoietic Stem Cell Transplantation for Children with Primary Immune Deficiency Disorders Indian Journal of Pediatrics. 04, 2021 | Pubmed ID: 33095397 Asymptomatic Reinfection in 2 Healthcare Workers From India With Genetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 11, 2021 | Pubmed ID: 32964927 A Rapid and Sensitive Method to Detect SARS-CoV-2 Virus Using Targeted-mass Spectrometry Journal of Proteins and Proteomics. 2020 | Pubmed ID: 33132628 Spectrum of Clinical Features and Genetic Variants in Mevalonate Kinase (MVK) Gene of South Indian Families Suffering from Hyperimmunoglobulin D Syndrome PloS One. 2020 | Pubmed ID: 32822427 Building the Vertebrate Codex Using the Gene Breaking Protein Trap Library ELife. 08, 2020 | Pubmed ID: 32779569 Maternal Vitamin B Deficiency in Rats Alters DNA Methylation in Metabolically Important Genes in Their Offspring Molecular and Cellular Biochemistry. May, 2020 | Pubmed ID: 32189172 Histone Variant Dictates Fate Biasing of Neural Crest Cells to Melanocyte Lineage Development (Cambridge, England). 03, 2020 | Pubmed ID: 32098766 Role of Tmem163 in Zinc-regulated Insulin Storage of MIN6 Cells: Functional Exploration of an Indian Type 2 Diabetes GWAS Associated Gene Biochemical and Biophysical Research Communications. 02, 2020 | Pubmed ID: 31813547 A Temporal Map of Gene Expression Pattern During Zebrafish Liver Regeneration Zebrafish. 02, 2020 | Pubmed ID: 31770088 PH-controlled Histone Acetylation Amplifies Melanocyte Differentiation Downstream of MITF EMBO Reports. 01, 2020 | Pubmed ID: 31709752 Saliva Microbiome in Primary Sjögren's Syndrome Reveals Distinct Set of Disease-associated Microbes Oral Diseases. Mar, 2020 | Pubmed ID: 31514257 Genomics of Rare Genetic Diseases-experiences from India Human Genomics. 09, 2019 | Pubmed ID: 31554517 Investigating Coronary Artery Disease Methylome Through Targeted Bisulfite Sequencing Gene. Dec, 2019 | Pubmed ID: 31499127 Loss of Function Mutation in the P2X7, a Ligand-gated Ion Channel Gene Associated with Hypertrophic Cardiomyopathy Purinergic Signalling. 06, 2019 | Pubmed ID: 31152337 A Novel Cathepsin D Mutation in 2 Siblings with Late Infantile Neuronal Ceroid Lipofuscinosis Neurology. Genetics. Jun, 2019 | Pubmed ID: 31086824 A Genome-wide Map of Circular RNAs in Adult Zebrafish Scientific Reports. 03, 2019 | Pubmed ID: 30837568 Methods to Study Long Noncoding RNA Expression and Dynamics in Zebrafish Using RNA Sequencing Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30635891 Methods for Annotation and Validation of Circular RNAs from RNAseq Data Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30635890 Knockdown of Calcium-binding Calb2a and Calb2b Genes Indicates the Key Regulator of the Early Development of the Zebrafish, Danio Rerio Brain Structure & Function. Mar, 2019 | Pubmed ID: 30460553 Identification of Novel Circadian Transcripts in the Zebrafish Retina The Journal of Experimental Biology. 01, 2019 | Pubmed ID: 30446534 Organellar Transcriptome Sequencing Reveals Mitochondrial Localization of Nuclear Encoded Transcripts Mitochondrion. 05, 2019 | Pubmed ID: 29486245 Large Scale Changes in the Transcriptome of Eisenia Fetida During Regeneration PloS One. 2018 | Pubmed ID: 30260966 Whole Exome Sequencing in a Multi-generation Family from India Reveals a Genetic Variation C.10C>T (p.Gln4Ter) in Keratin 5 Gene Associated with Dowling-Degos Disease Indian Journal of Dermatology, Venereology and Leprology. May-Jun, 2018 | Pubmed ID: 29600799 RNA Secondary Structure Profiling in Zebrafish Reveals Unique Regulatory Features BMC Genomics. 02, 2018 | Pubmed ID: 29448945 STIM1 Activation of Adenylyl Cyclase 6 Connects Ca and CAMP Signaling During Melanogenesis The EMBO Journal. 03, 2018 | Pubmed ID: 29311116 RNA Sequencing of Db/db Mice Liver Identifies LncRNA H19 As a Key Regulator of Gluconeogenesis and Hepatic Glucose Output Scientific Reports. 08, 2017 | Pubmed ID: 28814771 Classical Autophagy Proteins LC3B and ATG4B Facilitate Melanosome Movement on Cytoskeletal Tracks Autophagy. Aug, 2017 | Pubmed ID: 28598240 Neuroanatomical Demonstration of Calbindin 2a- and Calbindin 2b-like Calcium Binding Proteins in the Early Embryonic Development of Zebrafish: MRNA Study International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Aug, 2017 | Pubmed ID: 28396290 Egyptian Tale from India: Application of Whole-exome Sequencing in Diagnosis of Atypical Familial Mediterranean Fever International Journal of Rheumatic Diseases. Feb, 2017 | Pubmed ID: 28211254 Case Report: Whole Exome Sequencing Identifies Variation C.2308G>A P.E770K in Associated with B- T- NK+ Severe Combined Immunodeficiency F1000Research. 2016 | Pubmed ID: 29067161 Case Report: Application of Whole Exome Sequencing for Accurate Diagnosis of Rare Syndromes of Mineralocorticoid Excess F1000Research. 2016 | Pubmed ID: 29067160 Case Report: Whole Exome Sequencing Identifies a Novel Frameshift Insertion C.1325dupT (p.F442fsX2) in the Tyrosine Kinase Domain of Gene in a Young Indian Individual with X-linked Agammaglobulinemia F1000Research. 2016 | Pubmed ID: 28928935 Case Report: Whole Exome Sequencing Reveals a Novel Frameshift Deletion Mutation P.G2254fs in COL7A1 Associated with Autosomal Recessive Dystrophic Epidermolysis Bullosa F1000Research. 2016 | Pubmed ID: 27408687 Development of a Fluorescent Transgenic Zebrafish Biosensor for Sensing Aquatic Heavy Metal Pollution Transgenic Research. 10, 2016 | Pubmed ID: 27120052 Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding PLoS Genetics. Apr, 2016 | Pubmed ID: 27082250 Aptamer-Assisted Detection of the Altered Expression of Estrogen Receptor Alpha in Human Breast Cancer PloS One. 2016 | Pubmed ID: 27043307 Chamber Specific Gene Expression Landscape of the Zebrafish Heart PloS One. 2016 | Pubmed ID: 26815362 Case Report: Whole Exome Sequencing Helps in Accurate Molecular Diagnosis in Siblings with a Rare Co-occurrence of Paternally Inherited 22q12 Duplication and Autosomal Recessive Non-syndromic Ichthyosis F1000Research. 2015 | Pubmed ID: 26594337 ZflncRNApedia: A Comprehensive Online Resource for Zebrafish Long Non-Coding RNAs PloS One. 2015 | Pubmed ID: 26065909 Screening Currency Notes for Microbial Pathogens and Antibiotic Resistance Genes Using a Shotgun Metagenomic Approach PloS One. 2015 | Pubmed ID: 26035208 Exome Sequencing of Patients with Histiocytoid Cardiomyopathy Reveals a De Novo NDUFB11 Mutation That Plays a Role in the Pathogenesis of Histiocytoid Cardiomyopathy American Journal of Medical Genetics. Part A. Sep, 2015 | Pubmed ID: 25921236 Comparative Whole-genome Analysis of Clinical Isolates Reveals Characteristic Architecture of Mycobacterium Tuberculosis Pangenome PloS One. 2015 | Pubmed ID: 25853708 Erratum for Behera Et Al., Draft Genome Sequence of the Extremely Halophilic Bacterium Halomonas Salina Strain CIFRI1, Isolated from the East Coast of India Genome Announcements. 02, 2015 | Pubmed ID: 25700399 Mit-o-matic: a Comprehensive Computational Pipeline for Clinical Evaluation of Mitochondrial Variations from Next-generation Sequencing Datasets Human Mutation. Apr, 2015 | Pubmed ID: 25677119 Draft Genome Sequence of the Extremely Halophilic Bacterium Halomonas Salina Strain CIFRI1, Isolated from the East Coast of India Genome Announcements. Jan, 2015 | Pubmed ID: 25573926 Exome Sequencing Reveals a Novel Mutation, P.L325H, in the KRT5 Gene Associated with Autosomal Dominant Epidermolysis Bullosa Simplex Koebner Type in a Large Family from Western India Human Genome Variation. 2014 | Pubmed ID: 27081501 Short Stories on Zebrafish Long Noncoding RNAs Zebrafish. Dec, 2014 | Pubmed ID: 25110965 Non-coding RNA Based Regulation of Blood Vessel Development in Zebrafish and Relevance to Humans Molecular Cytogenetics. 2014 | Pubmed ID: 24940357 Human 45,X Fibroblast Transcriptome Reveals Distinct Differentially Expressed Genes Including Long Noncoding RNAs Potentially Associated with the Pathophysiology of Turner Syndrome PloS One. 2014 | Pubmed ID: 24932682 The Zebrafish GenomeWiki: a Crowdsourcing Approach to Connect the Long Tail for Zebrafish Gene Annotation Database : the Journal of Biological Databases and Curation. 2014 | Pubmed ID: 24578356 Draft Genome Sequence of Urease-Producing Sporosarcina Pasteurii with Potential Application in Biocement Production Genome Announcements. Jan, 2014 | Pubmed ID: 24482521 Morphological Effects of G-quadruplex Stabilization Using a Small Molecule in Zebrafish Biochemistry. Feb, 2014 | Pubmed ID: 24476096 Dynamic Expression of Long Non-coding RNAs (lncRNAs) in Adult Zebrafish PloS One. 2013 | Pubmed ID: 24391796 Time for the Zebrafish ENCODE Journal of Genetics. Dec, 2013 | Pubmed ID: 24371190 Draft Genome Sequence of a Multidrug-Resistant Clinical Isolate of Mycobacterium Tuberculosis Belonging to a Novel Spoligotype Genome Announcements. Nov, 2013 | Pubmed ID: 24265496 Draft Genome Sequence of Multidrug-Resistant Mycobacterium Tuberculosis Clinical Isolate OSDD515, Belonging to the Uganda I Genotype Genome Announcements. Nov, 2013 | Pubmed ID: 24265488 Draft Genome Sequence of an Extensively Drug-Resistant Mycobacterium Tuberculosis Clinical Isolate of the Ural Strain OSDD493 Genome Announcements. Nov, 2013 | Pubmed ID: 24201204 Systematic Pharmacogenomics Analysis of a Malay Whole Genome: Proof of Concept for Personalized Medicine PloS One. 2013 | Pubmed ID: 24009664 Draft Genome Sequence of a Clinical Isolate of Multidrug-Resistant Mycobacterium Tuberculosis East African Indian Strain OSDD271 Genome Announcements. Aug, 2013 | Pubmed ID: 23908284 LncRNome: a Comprehensive Knowledgebase of Human Long Noncoding RNAs Database : the Journal of Biological Databases and Curation. 2013 | Pubmed ID: 23846593 A Sequence-based Variation Map of Zebrafish Zebrafish. Mar, 2013 | Pubmed ID: 23590399 MiR-34 is Maternally Inherited in Drosophila Melanogaster and Danio Rerio Nucleic Acids Research. Apr, 2013 | Pubmed ID: 23470996 Systematic Transcriptome Wide Analysis of LncRNA-miRNA Interactions PloS One. 2013 | Pubmed ID: 23405074 Reverse Genetics Screen in Zebrafish Identifies a Role of MiR-142a-3p in Vascular Development and Integrity PloS One. 2012 | Pubmed ID: 23285103 Conceptual Approaches for LncRNA Drug Discovery and Future Strategies Expert Opinion on Drug Discovery. Jun, 2012 | Pubmed ID: 22559214 A Case for Pharmacogenomics in Management of Cardiac Arrhythmias Indian Pacing and Electrophysiology Journal. Mar, 2012 | Pubmed ID: 22557843 High Resolution Methylome Map of Rat Indicates Role of Intragenic DNA Methylation in Identification of Coding Region PloS One. 2012 | Pubmed ID: 22355382 Antagonism of MicroRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes) Chembiochem : a European Journal of Chemical Biology. Mar, 2012 | Pubmed ID: 22315191 De Novo Identification of Viral Pathogens from Cell Culture Hologenomes BMC Research Notes. Jan, 2012 | Pubmed ID: 22226071 Proteomic Analysis of Zebrafish (Danio Rerio) Embryos Exposed to Cyclosporine A Journal of Proteomics. Jan, 2012 | Pubmed ID: 22079245 Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish Babita Sharma*1,2, Yogaspoorthi J. Subramaniam*1,2, Desingu Ayyappa Raja1,2,3, Ayush Aggarwal1,2, Sridhar Sivasubbu1, Vivek T. Natarajan1,2 1CSIR-Institute of Genomics and Integrative Biology, 2Academy of Scientific and Innovative Research, 3Division of Biology and Biological Engineering, California Institute of Technology JoVE 62955 生物学
Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish Babita Sharma*1,2, Yogaspoorthi J. Subramaniam*1,2, Desingu Ayyappa Raja1,2,3, Ayush Aggarwal1,2, Sridhar Sivasubbu1, Vivek T. Natarajan1,2 1CSIR-Institute of Genomics and Integrative Biology, 2Academy of Scientific and Innovative Research, 3Division of Biology and Biological Engineering, California Institute of Technology JoVE 62955 生物学