Overview
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early embryonic development stage, teratogens can kill some of the cells in the blastocyst, resulting in the death of the embryo. Organogenesis is a well-defined sequence of events during embryonic development, where the cells of the embryo differentiate and organize themselves into distinct organs and organ systems.. Exposure to the teratogen at a particular time period produces specific organ malfunction. During histogenesis and functional maturation of the fetus, teratogens interfere with the pregnant woman's nutrient supply or hormonal balance. This indirectly results in functional and developmental abnormalities. For example, angiotensin II has an important role in renal function and the development of the fetus. Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor antagonists cause fetal malformation when administered in the early stages of pregnancy as well as oligohydramnios and renal failure in the later stages.…
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Embed code vs URL
An embed code allows you to place a JoVE video directly inside of your learning or training environment. Most learning management systems such as Canvas, Blackboard, and Moodle require an embed code for JoVE content to stream.
A URL allows you to place a link in programs such as PowerPoint or Microsoft Word which takes a user to a separate page where they can watch a JoVE video.
Most of the time, you will want to use the embed code. However, there are some environments that don’t support embed codes such as Google Classrooms and MS Teams. In those instances, you can use a URL to still provide access to JoVE videos.
What is an Embed Code?
Basically, it’s a snippet of code that you put on your website that displays as a video. An embed code pulls the video from the original source, allowing you to display a video without having to host the file on your website.
How to embed a video
STEP 1: COPY YOUR EMBED CODE
To generate the embed code, simply click the Copy button above. You can customize it by choosing a specific language for the video, or setting exact dimensions for the video player.
STEP 2: PASTE THE EMBED CODE INTO YOUR ENVIRONMENT
Embed codes can be used in most learning management systems (Canvas, Blackboard, Moodle…), organizational websites, and a host of other tools. The specifics of how to add in an embed code will depend on your environment.
Generally, it involves accessing a text editor, entering the HTML mode on the editor, and pasting in the embed code. Get more details on embedding into specific environments here.