Aortic Segments
Aortic Segments - Related Videos
09:12
Aortic Ring Assay
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Cited by 42 •
2009
Angiogenesis, the sprouting of blood vessels from pre-existing vasculature, is associated with both natural and pathological processes. Here we demonstrate an aortic ring assay that allows angiogenic potentiators and inhibitors to be directly added to aortic rings in culture. Sprouting and neovessel outgrowth can be determined by inspecting the aortic rings over a period of 6-12 days.
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Cited by 4 •
2017
Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.
08:20
Isolation and Primary Culture of Mouse Aortic Endothelial Cells
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Cited by 75 •
2016
The vascular endothelial cells play a significant role in many important cardiovascular disorders. This article describes a simple method to isolate and expand endothelial cells from the mouse aorta without using any special equipment. Our protocol provides an effective means of identifying mechanisms in endothelial cell physiopathology.
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
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Cited by 3 •
2013
Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion pathobiology.
08:25
Transverse Aortic Constriction in Mice
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Cited by 262 •
2010
Transverse aortic constriction (TAC) in the mouse is a commonly used experimental model to study mechanisms underlying cardiac hypertrophy and heart failure development. Here, we describe procedures to constrict the aorta to create a reproducible degree of cardiac hypertrophy in mice.
FAQs
Elastic recoil converts the aorta’s stretch during ventricular contraction into support for flow between beats. When the left ventricle contracts, the aortic wall expands to accommodate the incoming blood; as contraction ends, the wall recoils. This behavior explains why aortic segments contribute not only to transport but also to maintaining relatively continuous systemic circulation.
Segment-specific anatomy matters because each region has distinct relationships with neighboring structures and branch vessels. The aortic arch, for example, distributes blood toward the head and upper limbs, whereas the descending course continues through the thoracic and abdominal regions. Mapping these relationships helps connect vessel position with the systemic territories it serves.
Although the segments form one continuous vessel, their anatomical labels separate the root, ascending portion, arch, and descending course for analysis. That separation is useful when considering aneurysms or dissections, because the disease context can be related to a particular region rather than treated as an undifferentiated feature of the entire aorta. The segmental framework sharpens cardiovascular interpretation.
A segment-based review begins by tracing the vessel from the aortic root through the ascending aorta and arch, then along the descending thoracic and abdominal regions. The investigator records nearby structures and branch vessels at each stage, while also considering wall expansion and recoil. This workflow creates a consistent anatomical framework for biology, imaging, and disease-focused studies.
Vascular imaging benefits from segmental organization because observations can be assigned to recognizable portions of the aorta. A study can describe findings in relation to the root, ascending aorta, arch, or descending regions, while considering associated branches and neighboring anatomy. This approach supports interpretation by connecting an image with cardiovascular structure and function.
In developmental biology, the segment map provides a way to study how the aorta is organized along its course and how its relationships with branches and nearby structures contribute to cardiovascular anatomy. In clinical biology, the same framework supports study of blood pressure, aneurysms, and dissections. One anatomical scheme therefore links development, function, imaging, and disease.