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Journal / Biochemistry / Rab10 fosforylering detektion av LRRK2 aktivitet…
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Biochemistry

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JoVE Journal Biochemistry
Rab10 fosforylering detektion av LRRK2 aktivitet med SDS-PAGE med en fosfat-bindande tagg
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Rab10 fosforylering detektion av LRRK2 aktivitet med SDS-PAGE med en fosfat-bindande tagg

Article DOI: 10.3791/56688-v • 08:55 min • December 14th, 2017
December 14th, 2017 •
1, 1,2
1Laboratory of Brain and Neurological Disorders, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo

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Föreliggande studie beskriver en enkel metod för att upptäcka endogena nivåerna av Rab10 fosforylering av leucin-rika upprepa kinase 2.

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Biokemi fråga 130 Parkinsons sjukdom leucin-rika upprepa kinase 2 Rab10 fosforylering Phos-tag SDS-PAGE immunoblotting
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