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Bioengineering

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JoVE Journal Bioengineering
Progettazione di uno stent tracheale biocompatibile che epelle la droga nei topi con stenosi lariosa
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Progettazione di uno stent tracheale biocompatibile che epelle la droga nei topi con stenosi lariosa

Article DOI: 10.3791/60483-v • 08:26 min • January 21st, 2020
January 21st, 2020 •
1, 2, 2, 2, 2, 2, 2
1Department of General Surgery, University of California, San Francisco, 2Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine

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La stenosi larifica deriva da una deposizione di cicatrici patologiche che restringe criticamente le vie aeree tracheali e manca di terapie mediche efficaci. Utilizzando uno stent PLLA-PCL (70% poli-L-lactide e 30% policaprolactone) come sistema locale di somministrazione di farmaci, possono essere studiate potenziali terapie volte a ridurre la proliferazione della cicatrice nella trachea.

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Bioingegneria Numero 155 stent per l'uso di farmaci PLLA-PCL rapamicina stenosi lacrimotrale stenosi tracheale fibrosi
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