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Journal / Immunology and Infection / Transfección eficiente del ARNm transcrito in…
JoVE Journal
Immunology and Infection

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Transfección eficiente del ARNm transcrito in vitro en células cultivadas utilizando nanopartículas de péptido-poloxamina

Article DOI: 10.3791/64288-v • 10:16 min • August 17th, 2022
August 17th, 2022 •
*1, *1, 1, 1, 1, 1, 1, 2, 1, 3, 1
1National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, Third Military Medical University, 2Department of Pediatrics, Ludwig-Maximilians University of Munich, 3Department of Pharmacy, Southwest Hospital, Third Military Medical University
* These authors contributed equally

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Se desarrolla una nanopartícula de péptido-poloxamina autoensamblada (PP-sNp) utilizando un dispositivo de mezcla microfluídica para encapsular y entregar ARN mensajero transcrito in vitro . El ARNm/PP-sNp descrito podría transfectar eficientemente células cultivadas in vitro.

Tags

Inmunología e infección Número 186 Entrega de genes ARN mensajero transcrito in vitro sistemas de administración poloxamina nanopartícula
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