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JoVE Journal Biology
Genome Redigering med CompoZr tilpassede zink finger Nucleaser (ZFNs)
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Genome Redigering med CompoZr tilpassede zink finger Nucleaser (ZFNs)

Article DOI: 10.3791/3304-v • 09:11 min • June 14th, 2012
June 14th, 2012 •
1, 1, 1, 1, 1, 1
1Emerging Technologies, Sigma Life Science

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Den CompoZr tilpassede zink-finger-nuklease (ZFN) Service muliggør præcis genom redigering i en organisme eller celle linie ved ethvert sted defineret af brugeren. Denne artikel beskriver processen for konstruktion, fremstilling, validering og implementering af CompoZr Brugerdefineret ZFN Service.

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Genetik Molekylærbiologisk Institut Zink Finger nuklease Genome Engineering Genomisk redigering Gene Ændring Gene Knockout Gene integration ikke-homologe ende sammenføjning homolog rekombination målrettet genom redigering
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