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A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Article DOI: 10.3791/55277-v • 10:00 min • September 16th, 2017
September 16th, 2017 •
*1, *2, 1, 2, 1
1School of Experimental Psychology and Clinical Research and Imaging Center Bristol, University of Bristol, 2Department of Neurobiology, A.I. Virtanen Institute, University of Eastern Finland
* These authors contributed equally

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A protocol for stroke onset time estimation in a rat model of stroke exploiting quantitative magnetic resonance imaging (qMRI) parameters is described. The procedure exploits diffusion MRI for delineation of the acute stroke lesion and quantitative T1 and T2 (qT1 and qT2) relaxation times for timing of stroke.

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Magnetic Resonance Imaging (MRI) Stroke Onset Time Estimation Permanent Cerebral Ischemia Apparent Diffusion Coefficient (ADC) Acute Ischemic Stroke Detection T1 And T2 Relaxation Times Rat Model Of Ischemic Stroke Linear Function Semi-automated Computer Routine Hyperacute Phase Permanent Focal Ischemia Wistar Rats Middle Cerebral Artery Occlusion Isoflurane Anesthesia Common Carotid Artery (CCA)
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