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En Cell kultur modell av motstånd artärer

Article DOI: 10.3791/55992-v • 10:54 min • September 8th, 2017
September 8th, 2017 •
1,2, 3, 4, 3, 1,2
1Department of Molecular Physiology and Biophysics, University of Virginia School of Medicine, 2Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, 3Department of Hematology, St. Jude Children's Research Hospital, 4Research Histology Core, University of Virginia School of Medicine

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En cell kultur modell av motstånd artärer beskrivs, vilket möjliggör dissektion av signalering vägar i endotel, glatt muskulatur, eller mellan endotel och glatt muskulatur (myoendothelial korsningen). Selektiv tillämpning av agonister eller protein isolering, elektronmikroskopi eller immunofluorescens kan utnyttjas med hjälp av denna cell kultur modell.

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Medicin fråga 127 endotelceller glatta muskelcellen heterocellular kommunikation cell polaritet gap-junctions cellulära prognoser extracellulär matrix samtidig kultur
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