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En screeningmetode til identifikation af heterokratinfremmende stoffer ved hjælp af Drosophila

Article DOI: 10.3791/60917-v • 06:22 min • March 12th, 2020
March 12th, 2020 •
1, 1, 1, 1, 1, 1, 1
1Department of Medicine, University of California San Diego

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Drosophila er en udbredt eksperimentel model egnet til screening narkotika med potentielle ansøgninger om kræftbehandling. Her beskriver vi brugen af Drosophila brogede øjenfarvefænotyper som en metode til screening af små molekyleforbindelser, der fremmer heterochromatindannelse.

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Genetik heterochromatin tumor undertrykkelse små-molekyle forbindelser narkotika screening heterochromatin-fremme nde stof cellespredning Drosophila larver Drosophila celler voksen Drosophila position-effekt variegation
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