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Bescherming van H9c2 myocardiale cellen tegen oxidatieve stress door crocetine via PINK1 / Parkin Pathway-gemedieerde mitofagie

Article DOI: 10.3791/65105-v • 07:40 min • May 26th, 2023
May 26th, 2023 •
1, 1, 1, 1, 1, 1, 1,2
1School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, 2Fangshan Chinese Medicine Hospital, Beijing University of Chinese Medicine

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Op basis van in vitro experimenten onthulde deze studie het mechanisme van crocetine bij het repareren van oxidatieve stressschade van cardiomyocyten door mitofagie te beïnvloeden, waarbij de PINK1 / Parkin-signaleringsroute een belangrijke rol speelt.

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Geneeskunde crocetine H9c2 myocardcellen oxidatieve stress PINK1/Parkin pathway mitofagie
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