Hiroshi Kawamoto Department of Surgery, Graduate School of Medicine Kyoto University Biography Publications Institution JoVE Articles Hiroshi Kawamoto has not added a biography. If you are Hiroshi Kawamoto and would like to personalize this page please email our Author Liaison for assistance. Publications Evolutionary Reversion in Tumorigenesis Frontiers in Oncology. 2023 | Pubmed ID: 38023242 Regulation of Lymphoid-myeloid Lineage Bias Through Regnase-1/3-mediated Control of Nfkbiz Blood. Nov, 2023 | Pubmed ID: 37922454 SETBP1 is Dispensable for Normal and Malignant Hematopoiesis Leukemia. Sep, 2023 | Pubmed ID: 37464069 [Development of "Off the Shelf" T Cells for Cancer Immunotherapy] Gan to Kagaku Ryoho. Cancer & Chemotherapy. May, 2023 | Pubmed ID: 37218312 Characteristic Differences in the Abundance of Tumor-infiltrating Lymphocytes and Intratumoral Developing T Cells in Thymoma, with Special Reference to PD-1 Expression Cancer Immunology, Immunotherapy : CII. Aug, 2023 | Pubmed ID: 37060363 Murine Breast Cancers Disorganize the Liver Transcriptome in a Zonated Manner Communications Biology. Jan, 2023 | Pubmed ID: 36694005 Tracing the Evolutionary History of Blood Cells to the Unicellular Ancestor of Animals Blood. Dec, 2022 | Pubmed ID: 36112959 Aberrant EVI1 Splicing Contributes to EVI1-rearranged Leukemia Blood. Aug, 2022 | Pubmed ID: 35709354 Remote Solid Cancers Rewire Hepatic Nitrogen Metabolism Via Host Nicotinamide-N-methyltransferase Nature Communications. 06, 2022 | Pubmed ID: 35705545 Propionic Acid, Induced in Gut by an Inulin Diet, Suppresses Inflammation and Ameliorates Liver Ischemia and Reperfusion Injury in Mice Frontiers in Immunology. 2022 | Pubmed ID: 35572528 Increase in the Incidence of Acute Inflammatory Reactions to Injectable Fillers During COVID-19 Era Journal of Cosmetic Dermatology. May, 2022 | Pubmed ID: 35218285 Isolation of TCR Genes with Tumor-killing Activity from Tumor-infiltrating and Circulating Lymphocytes in a Tumor Rejection Cynomolgus Macaque Model Molecular Therapy Oncolytics. Mar, 2022 | Pubmed ID: 35024435 CD153/CD30 Signaling Promotes Age-dependent Tertiary Lymphoid Tissue Expansion and Kidney Injury The Journal of Clinical Investigation. Jan, 2022 | Pubmed ID: 34813503 Regeneration of Antigen-specific T Cells by Using Induced Pluripotent Stem Cell (iPSC) Technology International Immunology. Nov, 2021 | Pubmed ID: 34661676 [The Origin of Blood Cells and Myeloid Cells] [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. 2021 | Pubmed ID: 34248129 Possible NK Cell-mediated Immune Responses Against IPSC-derived Cells in Allogeneic Transplantation Settings Inflammation and Regeneration. Jan, 2021 | Pubmed ID: 33407951 A Regulatory Element in the 3'-untranslated Region of CEBPA is Associated with Myeloid/NK/T-cell Leukemia European Journal of Haematology. Mar, 2021 | Pubmed ID: 33197296 [Mass-Production of Cytotoxic T Lymphocytes Regenerated from Pluripotent Stem Cells-To Target Solid Tumors] Gan to Kagaku Ryoho. Cancer & Chemotherapy. Oct, 2020 | Pubmed ID: 33130732 Regeneration of Tumor-Antigen-Specific Cytotoxic T Lymphocytes from IPSCs Transduced with Exogenous TCR Genes Molecular Therapy. Methods & Clinical Development. Dec, 2020 | Pubmed ID: 33102617 Cytotoxic T Lymphocytes Regenerated from IPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model IScience. Apr, 2020 | Pubmed ID: 32259478 Long Non-coding RNA MANCR is a Target of BET Bromodomain Protein BRD4 and Plays a Critical Role in Cellular Migration and Invasion Abilities of Prostate Cancer Biochemical and Biophysical Research Communications. May, 2020 | Pubmed ID: 32199616 High Frequency Production of T Cell-Derived IPSC Clones Capable of Generating Potent Cytotoxic T Cells Molecular Therapy. Methods & Clinical Development. Mar, 2020 | Pubmed ID: 31970197 [Mass-Production of Tumor Antigen-Specific Cytotoxic T Lymphocytes Using the IPS Cell Technology-Development of "Off-the-Shelf T Cells"for the Use in Allogeneic Transfusion Settings] Gan to Kagaku Ryoho. Cancer & Chemotherapy. Nov, 2019 | Pubmed ID: 31748471 Identification of a Genomic Enhancer That Enforces Proper Apoptosis Induction in Thymic Negative Selection Nature Communications. 06, 2019 | Pubmed ID: 31197149 Novel Hybrid Three-dimensional Artificial Liver Using Human Induced Pluripotent Stem Cells and a Rat Decellularized Liver Scaffold Regenerative Therapy. Jun, 2019 | Pubmed ID: 31032388 Secreted PD-L1 Variants Mediate Resistance to PD-L1 Blockade Therapy in Non-small Cell Lung Cancer The Journal of Experimental Medicine. Apr, 2019 | Pubmed ID: 30872362 Suppression Effect on IFN-γ of Adipose Tissue-derived Mesenchymal Stem Cells Isolated from β2-microglobulin-deficient Mice Experimental and Therapeutic Medicine. Nov, 2018 | Pubmed ID: 30344701 Three-step Transcriptional Priming That Drives the Commitment of Multipotent Progenitors Toward B Cells Genes & Development. 01, 2018 | Pubmed ID: 29440259 Cloning and Expansion of Antigen-specific T Cells Using IPS Cell Technology: Development of "off-the-shelf" T Cells for the Use in Allogeneic Transfusion Settings International Journal of Hematology. Mar, 2018 | Pubmed ID: 29388165 NK Cell Alloreactivity Against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous IPSCs Stem Cell Reports. 09, 2017 | Pubmed ID: 28867344 Recurrent SPI1 (PU.1) Fusions in High-risk Pediatric T Cell Acute Lymphoblastic Leukemia Nature Genetics. Aug, 2017 | Pubmed ID: 28671687 The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development Immunity. 05, 2017 | Pubmed ID: 28514688 Conversion of T Cells to B Cells by Inactivation of Polycomb-mediated Epigenetic Suppression of the B-lineage Program Genes & Development. 11, 2016 | Pubmed ID: 27913604 Regeneration of CD8αβ T Cells from T-cell-Derived IPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity Cancer Research. 12, 2016 | Pubmed ID: 27872100 Heterogeneous Fibroblasts Underlie Age-dependent Tertiary Lymphoid Tissues in the Kidney JCI Insight. 07, 2016 | Pubmed ID: 27699223 Regeneration of Tumor Antigen-specific CTLs Utilizing IPS Technology [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. 08, 2016 | Pubmed ID: 27599425 Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting Applied Biochemistry and Biotechnology. Dec, 2016 | Pubmed ID: 27406037 Aberrant PD-L1 Expression Through 3'-UTR Disruption in Multiple Cancers Nature. 06, 2016 | Pubmed ID: 27281199 Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells PLoS Genetics. Jan, 2016 | Pubmed ID: 26789017 Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells Stem Cell Reports. Nov, 2015 | Pubmed ID: 26607950 CNOT3 Contributes to Early B Cell Development by Controlling Igh Rearrangement and P53 MRNA Stability The Journal of Experimental Medicine. Aug, 2015 | Pubmed ID: 26238124 BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells Journal of Immunology (Baltimore, Md. : 1950). Aug, 2015 | Pubmed ID: 26136427 The E-Id Protein Axis Modulates the Activities of the PI3K-AKT-mTORC1-Hif1a and C-myc/p19Arf Pathways to Suppress Innate Variant TFH Cell Development, Thymocyte Expansion, and Lymphomagenesis Genes & Development. Feb, 2015 | Pubmed ID: 25691468 Indication for Neoadjuvant Chemotherapy in Patients with Colorectal Liver Metastases Based on a Nomogram That Predicts Disease-free Survival Journal of Hepato-biliary-pancreatic Sciences. Dec, 2014 | Pubmed ID: 25155418 TCF-1 and LEF-1 Act Upstream of Th-POK to Promote the CD4(+) T Cell Fate and Interact with Runx3 to Silence Cd4 in CD8(+) T Cells Nature Immunology. Jul, 2014 | Pubmed ID: 24836425 Differential Roles of Epigenetic Changes and Foxp3 Expression in Regulatory T Cell-specific Transcriptional Regulation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706905 Loss of MTOR Complex 1 Induces Developmental Blockage in Early T-lymphopoiesis and Eradicates T-cell Acute Lymphoblastic Leukemia Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2014 | Pubmed ID: 24567410 Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2 Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19380810 Regulation of T Cell Receptor Beta Gene Rearrangements and Allelic Exclusion by the Helix-loop-helix Protein, E47 Immunity. Dec, 2007 | Pubmed ID: 18093539 Impaired T-cell Differentiation in the Thymus at the Early Stages of Acute Pathogenic Chimeric Simian-human Immunodeficiency Virus (SHIV) Infection in Contrast to Less Pathogenic SHIV Infection Microbes and Infection. May, 2006 | Pubmed ID: 16702011 Prethymic T-cell Development Defined by the Expression of Paired Immunoglobulin-like Receptors The EMBO Journal. Dec, 2005 | Pubmed ID: 16292344 Intrathymic Effect of Acute Pathogenic SHIV Infection on T-lineage Cells in Newborn Macaques Microbiology and Immunology. 2005 | Pubmed ID: 16034211 Thymic Anlage is Colonized by Progenitors Restricted to T, NK, and Dendritic Cell Lineages Journal of Immunology (Baltimore, Md. : 1950). Mar, 2005 | Pubmed ID: 15728458 Analyses of Peripheral Blood Mononuclear Cells in Operational Tolerance After Pediatric Living Donor Liver Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Dec, 2004 | Pubmed ID: 15575917 Identification of the Earliest Prethymic T-cell Progenitors in Murine Fetal Blood Blood. Jan, 2004 | Pubmed ID: 14512296 T/NK Bipotent Progenitors in the Thymus Retain the Potential to Generate Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Oct, 2003 | Pubmed ID: 14500634 Antigen-driven T Cell Anergy and Defective Memory T Cell Response Via Deregulated Rap1 Activation in SPA-1-deficient Mice Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 12958214 Myeloproliferative Stem Cell Disorders by Deregulated Rap1 Activation in SPA-1-deficient Mice Cancer Cell. Jul, 2003 | Pubmed ID: 12892713 Extensive Proliferation of T Cell Lineage-restricted Progenitors in the Thymus: an Essential Process for Clonal Expression of Diverse T Cell Receptor Beta Chains European Journal of Immunology. Mar, 2003 | Pubmed ID: 12616481 The Common Myelolymphoid Progenitor: a Key Intermediate Stage in Hemopoiesis Generating T and B Cells Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12244141 Commitment to Natural Killer Cells Requires the Helix-loop-helix Inhibitor Id2 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2001 | Pubmed ID: 11296270 Commitment of Common T/Natural Killer (NK) Progenitors to Unipotent T and NK Progenitors in the Murine Fetal Thymus Revealed by a Single Progenitor Assay The Journal of Experimental Medicine. Dec, 1999 | Pubmed ID: 10587352 A Cell-autonomous Requirement for CXCR4 in Long-term Lymphoid and Myeloid Reconstitution Proceedings of the National Academy of Sciences of the United States of America. May, 1999 | Pubmed ID: 10318941 Author Spotlight: Exploring Cold Ischemia and Warm Reperfusion Injury in Fatty Liver Transplantation Kosuke Tanaka1, Yoichiro Uchida1, Shoichi Kageyama1, Kojiro Nakamura1, Hirofumi Hirao1, Kentaro Kadono1, Hiroshi Kawamoto1, Kenichi Saga1, Yuki Kidoguchi1, Takeshi Watanabe2, Etsuro Hatano1 1Department of Surgery, Graduate School of Medicine, Kyoto University, 2Institute for Frontier Life and Medical Sciences, Kyoto University JoVE 66215 Médecine Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells Meghan L. Good*1,2, Raul Vizcardo*1,2, Takuya Maeda1,2, Naritaka Tamaoki1,2, Parisa Malekzadeh1, Hiroshi Kawamoto3, Nicholas P. Restifo1,2 1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University JoVE 59997 Recherche en cancérologie
Author Spotlight: Exploring Cold Ischemia and Warm Reperfusion Injury in Fatty Liver Transplantation Kosuke Tanaka1, Yoichiro Uchida1, Shoichi Kageyama1, Kojiro Nakamura1, Hirofumi Hirao1, Kentaro Kadono1, Hiroshi Kawamoto1, Kenichi Saga1, Yuki Kidoguchi1, Takeshi Watanabe2, Etsuro Hatano1 1Department of Surgery, Graduate School of Medicine, Kyoto University, 2Institute for Frontier Life and Medical Sciences, Kyoto University JoVE 66215 Médecine
Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells Meghan L. Good*1,2, Raul Vizcardo*1,2, Takuya Maeda1,2, Naritaka Tamaoki1,2, Parisa Malekzadeh1, Hiroshi Kawamoto3, Nicholas P. Restifo1,2 1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University JoVE 59997 Recherche en cancérologie
