Motor Nerves

Motor nerves are bundles of nerve fibers that carry signals from the central nervous system to muscles and glands, enabling movement and other physiological responses. When the brain or spinal cord initiates an action, motor neurons transmit electrical impulses along their axons, and neurotransmitters released at neuromuscular junctions stimulate muscle fibers to contract. Motor nerves support voluntary actions such as walking and writing as well as involuntary functions, including heart activity and digestion through the autonomic nervous system. Studying their structure and signaling helps explain motor control, reflexes, neuromuscular disorders, and the effects of nerve injury in biology and medicine.

Motor Nerves - Related Videos

Research

JoVE EoE - Neuronal Culture Techniques

Developing Human iPSC-Derived Motor Nerve Organoids Using a Microfluidic Chip

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2025

This video demonstrates the method of creating motor nerve organoids by first culturing human induced pluripotent stem cells in a special medium to form spheroids, then differentiating them into motor neurons using specific inhibitors, and finally cultivating them in a microfluidic chip to extend axons and form motor nerve organoids.

Purification of Fibroblasts and Schwann Cells from Sensory and Motor Nerves in Vitro

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Cited by 7 •

2020

Here, we present a method to purify fibroblasts and Schwann cells from sensory and motor nerves in vitro.

Motor Nerve Transection and Time-lapse Imaging of Glial Cell Behaviors in Live Zebrafish

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Cited by 14 •

2013

Although the peripheral nervous system (PNS) is capable of significant repair after injury, little is known about the cellular and molecular mechanisms that govern this phenomenon. Using live, transgenic zebrafish and a reproducible nerve transection assay, we can study dynamic glial cell behaviors during nerve degeneration and regeneration.

Research

JoVE Journal - Neuroscience
Free Sample

Three-Dimensional Motor Nerve Organoid Generation

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Cited by 14 •

2020

This protocol provides a comprehensive procedure to fabricate human iPS cell-derived motor nerve organoid through spontaneous assembly of a robust bundle of axons extended from a spheroid in a tissue culture chip.

Research

JoVE Journal - Medicine
Free Sample

Structured Motor Rehabilitation After Selective Nerve Transfers

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Cited by 20 •

2019

Here, we present a protocol for the motor rehabilitation of patients with severe nerve injuries and selective nerve transfer surgery. It aims at restoring the motor function proposing several stages in patient education, early-stage therapy after surgery and interventions for rehabilitation after successful re-innervation of the nerve’s target.

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