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Polyakrylamidgeler for Invadopodia og trekkraft Analyser på kreftceller
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Polyakrylamidgeler for Invadopodia og trekkraft Analyser på kreftceller

Article DOI: 10.3791/52343-v • 08:48 min • January 4th, 2015
January 4th, 2015 •
1, 1
1Department of Otolaryngology, Vanderbilt University Medical Center

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Mekanisk stivhet i svulsten mikromiljøet spiller en avgjørende rolle i å drive ondartet oppførsel ved å øke invadopodia aktivitet og actomyosin kontraktilitet. Ved hjelp av polyakrylamidgeler (Paas), kan invadopodia og trekkraft analyser anvendes for å studere de invasive og kontraktile egenskaper av kreftceller i respons til matrise stivhet.

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Medisin invadopodia trekkraft degradering kontraktilitet stivhet polyakrylamid
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