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Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents
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Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Article DOI: 10.3791/58186-v • 06:59 min • August 14th, 2018
August 14th, 2018 •
1,2, 3, 4, 2
1College of Osteopathic Medicine, Michigan State University, 2Department of Orthopaedic Surgery, University of Michigan Medical School, 3Lymann Briggs College, Michigan State University, 4College of Engineering, Michigan State University

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The goal of the protocol is to optimize the fracture generation parameters to yield consistent fractures. This protocol accounts for the variations in bone size and morphology that may exist between animals. Additionally, a cost-effective, adjustable fracture apparatus is described.

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Fracture Apparatus Design Protocol Optimization Closed-stabilized Fractures Rodents Bone Biology Fracture Healing Consistent Fractures Radiographs Limb Femur Tibia Fractures Fracture Length Guillotine Impact Fracture Positioning Jig Depth U-shaped Channel Specimen Positioning Prone Position Supine Position Dorsum Of The Foot Guillotine Depression
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