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微生物肠道血屏障及肝脏代谢的体内评价方法
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微生物肠道血屏障及肝脏代谢的体内评价方法

Article DOI: 10.3791/58456-v • 14:54 min • October 20th, 2018
October 20th, 2018 •
1, 1, 1, 1, 2, 1
1Department of Experimental Physiology and Pathophysiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, 2Mass Spectrometry Laboratory, Institute of Biochemistry and Biophysics, Polish Academy of Sciences

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营养物质、微生物代谢物和药物进入血液循环的途径由肠道血屏障 (GBB) 控制。我们描述了一种直接测量体内 GBB 通透性的方法, 与常用的间接方法相比, 它几乎不受肝肾功能的影响。

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医学 问题 140 肠血屏障 肠道通透性 肝清除 门血取样 肠道细菌 TMA 短链脂肪酸
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