Chapter 29
Cell-Cell Interactions
Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical…
The cadherins were one of the first cell adhesion molecules discovered; the term “cadherins” is based on their…
The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of…
Catenins are characterized by multiple binding domains and dynamic structures that allow them to function as linker proteins in cell junction…
Cell adhesion is an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type,…
Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein…
The complex three-dimensional arrangement of cells in any multicellular organism is defined and maintained by interactions of cells with each other…
Strong contact points between adjacent cells anchor them to each other, forming tissues. Such anchoring junctions are of two types – …
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and…
The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first…
Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments…
The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap…
Cell-cell adhesion is fundamental to multicellular life and is mediated by a diverse array of cell surface proteins. However, the adhesive…
This protocol describes a scalpel loading-fluorescent dye transfer (SL-DT) technique that measures intercellular communication through gap junction…
Real-time Imaging of Endothelial Cell-cell Junctions During Neutrophil Transmigration Under Physiological Flow
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During inflammation, leukocytes leave the circulation and cross the endothelium to fight invading pathogens in underlying tissues. This process is…
