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Flow Cytometry and Data Analysis of Murine Brain Histone Post-Translational Modifications

Mouse Brain Histone Modification Quantification Using Flow Cytometry

Article DOI: 10.3791/200982-v • 02:23 min • September 15th, 2023
September 15th, 2023 •
1, 2, 1
1Department of Biochemistry and Molecular Biology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2Graduate Program in Neuroscience, Djavad Mowafaghian Centre for Brain Health, University of British Columbia

Tags

Quantification Global Histone Post-translational Modifications Intranuclear Flow Cytometry Isolated Mouse Brain Microglia Gene Expression Control Chromatin Structure Posttranslational Modifications Histone Tails Acetylation Lysine Residues DNA Interactions Transcription Factor Access Bromodomain-containing Transcriptional Activators Enhanced Gene Expression Dynamic Regulation Cell Differentiation Cellular Environments Stimuli Next-generation Sequencing Approaches High Throughput Quantitative Measure
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