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Journal / Bioengineering / 透明质酸基水凝胶对3维患者源性胶质瘤细胞培养的研究…
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Bioengineering

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JoVE Journal Bioengineering
透明质酸基水凝胶对3维患者源性胶质瘤细胞培养的研究
A Microfluidic Technique to Probe Cell Deformability
Journal (Bioengineering)
A Microfluidic Technique to Probe Cell Deformability
Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
Journal (Bioengineering)
Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
 
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透明质酸基水凝胶对3维患者源性胶质瘤细胞培养的研究

Article DOI: 10.3791/58176-v • 08:35 min • August 24th, 2018
August 24th, 2018 •
1, 1, 1, 2
1Department of Bioengineering, University of California, Los Angeles, 2Department of Bioengineering, Jonsson Comprehensive Cancer Center, Broad Stem Cell Research Center, Brain Research Institute, University of California, Los Angeles

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在这里, 我们提出了一个协议, 三维培养病人的胶质瘤细胞在正交可调谐生物材料设计, 以模仿大脑基质。这种方法提供了一种体外实验平台, 它能维持体内胶质瘤细胞的许多特征, 通常在培养中丢失。

Tags

生物工程 138 期 透明质酸 3D 培养 胶质瘤 微环境 细胞外基质 生物材料 美国匹茨堡 耐药性
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